Protein carbonylation: proteomics, specificity and relevance to aging

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dc.contributor.authorCabiscol Català, Elisa
dc.contributor.authorTamarit Sumalla, Jordi
dc.contributor.authorRos Salvador, Joaquim
dc.date.accessioned2016-05-06T08:24:24Z
dc.date.embargoEndDate2025-01-01
dc.date.issued2013
dc.description.abstractDetection and quantification of protein carbonyls present in biological samples has become a popular, albeit indirect, method to determine the existence of oxidative stress. Moreover, the rise of proteomics has allowed the identification of the specific proteins targeted by protein carbonylation. This review discusses these methodologies and proteomic strategies and then focuses on the relationship between protein carbonylation and aging and the parameters that may explain the increased sensitivity of certain proteins to protein carbonylation.ca_ES
dc.description.sponsorshipThis work has been supported by grants BFU 2010-19193, BFU2010-17387 and CSD2007-20 Consolider Ingenio 2010 from the Ministerio de Ciencia e Innovación (Spain) and SGR2009-00196 from the Generalitat de Catalunya.ca_ES
dc.identifier.doihttps://doi.org/10.1002/mas.21375
dc.identifier.idgrec019667
dc.identifier.issn0277-7037
dc.identifier.urihttp://hdl.handle.net/10459.1/56968
dc.language.isoengca_ES
dc.publisherWileyca_ES
dc.relationMICINN/PN2008-2011/BFU2010-19193
dc.relationMICINN/PN2008-2011/BFU2010-17387
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1002/mas.21375ca_ES
dc.relation.ispartofMass Spectrometry Reviews, 2013, vol. 33, núm. 1ca_ES
dc.rights(c) Wiley, 2013ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_ES
dc.subjectProtein carbonylationca_ES
dc.subjectAgingca_ES
dc.subjectProteomicsca_ES
dc.titleProtein carbonylation: proteomics, specificity and relevance to agingca_ES
dc.typearticleca_ES
dc.type.versionpublishedVersionca_ES
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