L'IRBLleida és un centre de recerca conjunt entre la Universitat i el Departament de Salut de la Generalitat de Catalunya. Té com a funció potenciar les sinergies de recerca biomèdica entre ambdós institucions i està compromès en avançar en la recerca biomèdica com a mitja per millorar la salut de la població i facilitar una activitat assistencial òptima en situacions de malaltia. [Més informació].

Collections in this community

Recent Submissions

  • Factors Influencing Nurse Assistants' Job Satisfaction in Nursing Homes in Canada and Spain: A Comparison of Two Cross-Sectional Observational Studies 

    McGilton, Katherine S.; Stewart, Steven; Bethell, Jennifer; Chu, Charlene H.; Mateos, José Tomás; Pastells Peiró, Roland; Blanco Blanco, Joan; Rodriguez-Monforte, Miriam; Escrig-Pinol, Astrid; Gea Sánchez, Montserrat (SAGE Publications, 2020-12-22)
    Objectives: To access associations between job satisfaction and supervisory support as moderated by stress. Methods: For this cross-sectional study, data collected from 591 nursing assistants in 42 nursing homes in Canada ...
  • Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease 

    Hernández-Alvarez, María Isabel; Sebastián, David; Vives, Sara; Ivanova, Sa ka; Bartoccioni, Paola; Kakimoto, Pamela; Plana, Natalia; Veiga, Sónia R.; Hernández, Vanessa; Vasconcelos, Nuno; Gopalacharyulu, Peddinti; Adrover, Anna; Jové Font, Mariona; Pamplona Gras, Reinald; Berenguer-Llergo, Antonio; Gordaliza, Isabel; Calvo, Enrique; Cabré, Noemí; Castro, Rui; Kuzmanic, Antonija; Boutant, Marie; Sala, David; Hyotylainen, Tuulia; Oresic, Matej; Fort, Joana; Errasti-Murugarren, Ekaitz; Orozco, Modesto; Joven, Jorge; Cantó, Carles; Palacin, Manuel; Fernández-Veledo, Sonia; Vendrell, Joan; Zorzano, Antonio (Elsevier, 2019-05-02)
    Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies ...
  • Biosynthesis de novo of glycerophospholipids and longevity 

    Mota Martorell, Natalia; Pradas Barriga, Irene; Jové Font, Mariona; Naudí i Farré, Alba; Pamplona Gras, Reinald (Sociedad Española de Geriatría y Gerontología, 2019-03-30)
    Introducción. Entre los principales componentes lipídicos de las membranas celulares se encuentran los glicerofosfolípidos (GFL), que se sintetizan en una vía de novo a partir del diacilglicerol (DAG). El perfil lipídico ...
  • Higher Accuracy of Lung Ultrasound over Chest X-ray for Early Diagnosis of COVID-19 Pneumonia 

    Martínez Redondo, Javier; Comas Rodríguez, Carles; Pujol Salud, Jesús; Crespo Pons, Montserrat; García Serrano, Cristina; Ortega Bravo, Marta; Palacín Peruga, Jose María (MDPI, 2021)
    Background: The COVID-19 pandemic rapidly strained healthcare systems worldwide. The reference standard for diagnosis is a positive reverse transcription polymerase chain reaction (RTPCR) test, but results are not immediate ...
  • Leading Factors for Weight Gain during COVID-19 Lockdown in a Spanish Population: A Cross-Sectional Study 

    Sánchez Peña, Enric; Lecube Torelló, Albert; Bellido, Diego; Monereo, Susana; Malagón, Maria Mar; Tinahones, Francisco José (MDPI, 2021)
    The increase in sedentary behaviors during the COVID-19-induced lockdown may have led to a significant weight gain. To investigate this hypothesis, a representative sample of the Spanish adult population comprising 1000 ...
  • Incidence of COVID-19 in patients exposed to chloroquine and hydroxychloroquine: results from a population-based prospective cohort in Catalonia, Spain, 2020 

    Vivanco-Hidalgo, Rosa Maria; Molina, Israel; Martinez, Elisenda; Roman-Viñas, Ramón; Sánchez-Montalvá, Adrián; Fibla Palazón, Joan; Pontes, Caridad; Velasco Muñoz, César (European Centre for Disease Prevention and Control, 2021)
    Background: Several clinical trials have assessed the protective potential of chloroquine and hydroxychloroquine. Chronic exposure to such drugs might lower the risk of infection with severe acute respiratory syndrome ...
  • Plyometric jump training effects on the physical fitness of individual-sport athletes: a systematic review with meta-analysis 

    Solé Cases, Silvia; Ramírez-Campillo, Rodrigo; Andrade, David C.; Sánchez-Sánchez, Javier (PeerJ, 2021-03-01)
    Background: The aim of this study is to conduct a systematic review with meta-analysis to explore the effects of plyometric jump training (PJT) on the physical fitness of individual sport athletes (ISA). Methods: Following ...
  • L1CAM expression in endometrial carcinomas: an ENITEC collaboration study 

    van der Putten, Louis J. M.; Visser, Nicole C.M.; van de Vijver, Koen; Santacana, Maria; Bronsert, Peter; Bulten, Johan; Hirschfeld, Marc; Colás, Eva; Gil-Moreno, Antonio; Garcia, Angel; Mancebo, Gemma; Alameda, Fransesc; Trovik, Jone; Kopperud, Reidun K.; Huvila, Jutta; Schrauwen, Stefanie; Koskas, Martin; Walker, Francine; Weinberger, Vit; Minar, Lubos; Jandakova, Eva; Snijders, Marc P. L. M.; van den Berg-van Erp, Saskia; Matias-Guiu, Xavier; Salvesen, Helga B.; Amant, Frederic; Massuger, Leon F. A. G.; Pijnenborg, Johanna M. A. (Springer Nature, 2016)
    Background: Identification of aggressive endometrioid endometrial carcinomas (EECs) and non-endometrioid carcinomas (NEECs) is essential to improve outcome. L1 cell adhesion molecule (L1CAM) expression is a strong prognostic ...
  • Further the liquid biopsy: Gathering pieces of the puzzle of genometastasis theory 

    García-Casas, Ana; García-Olmo, Dolores C.; García-Olmo, Damián (Baishideng Publishing Group, 2017)
    Metastasis is the major cause of mortality in cancer disease and still constitutes one of the most controversial mechanism, not yet fully understood. What is almost beyond doubt is that circulatory system is crucial for ...
  • Informed Consent Procedure in Clinical Trials Promoted by the Hospital: Knowledge and Perceptions of Primary Care Physicians 

    Gómez Arbonés, Javier; Salazar-Alarcon, E.; Solanilla Puertolas, Montserrat; Ortega Bravo, Marta; Vallez-Valero, L.; Schoenenberger, Joan Antoni (SciTech Central, 2020-07-20)
    Objectives: To evaluate Primary Care Physician's (PCP) awareness degree concerning their patient's participation in Clinical Trials (CT) analyze the communication methods used and obtain physicians personal views. Methods: ...
  • Clinico-epidemiological characteristics of men and women with a new diagnosis of chronic obstructive pulmonary disease: a database (SIDIAP) study 

    Montserrat i Capdevila, Josep; Marsal Mora, Josep Ramon; Ortega Bravo, Marta; Castañ, Maria Teresa; Alsedà Graells, Miquel; Barbé Illa, Ferran; Godoy i García, Pere (BioMed Central, 2021-01-28)
    Background: The risk of developing Chronic Obstructive Pulmonary Disease (COPD), the associated comorbidities and response to bronchodilators might differ in men and women. The objective of this study was to determine the ...
  • Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: randomised controlled trial 

    Durán-Cantolla, Joaquín; Aizpuru, Felipe; Montserrat, Josep Maria; Ballester, Eugeni; Terán, Joaquin; Aguirregomoscorta, Jose Ignacio; Gonzalez, Mónica; Lloberes, Patricia; Masa, Juan F.; Peña, Mónica de la; Carrizo, Santiago; Mayos, Mercè; Barbé Illa, Ferran (BMJ Publishing Group, 2010)
    Objective: To assess the effect of continuous positive airway pressure (CPAP) on 24 hour ambulatory blood pressure monitoring values in a large number of patients with untreated systemic hypertension of new onset and ...
  • A salmon peptide diet alleviates experimental colitis as compared with fish oil 

    Grimstad, Tore; Bjørndal, Bodil; Cacabelos Barral, Daniel; Aasprong, Ole G.; Omdal, Roald; Svardal, Asbjørn; Bohov, Pavol; Pamplona Gras, Reinald; Portero Otín, Manuel; Berge, Rolf K.; Hausken, Trygve (Cambridge University Press, 2013)
    Fish oil (FO) has been shown to have anti-inflammatory properties in animal models of inflammatory bowel disease, but how fish peptides (FP) influence intestinal inflammation has been less studied. Male Wistar rats, divided ...
  • Peritoneal Dialysis Is an Independent Factor Associated to Lower Intima Media Thickness in Dialysis Patients Free From Previous Cardiovascular Disease 

    Borràs, Mercè; Cambray Carner, Serafí; Crespo Masip, Maria; Pérez Fontán, Miguel; Bozić Stanojević, Milica; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira; Betriu i Bars, M. Àngels; Valdivielso Revilla, José Manuel (Frontiers Media, 2018)
  • Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2- negative breast cancer 

    Fernandez-Martinez, Aranzazu; Pascual, Tomás; Perrone, Giuseppe; Morales Murillo, Serafín; de la Haba, Juan; González-Rivera, Milagros; Galván, Patricia; Zalfa, Francesca; Amato, Michela; Gonzalez, Lucia; Prats, Miquel; Rojo, Federico; Manso, Luis; Paré, Laia; Alonso, Immaculada; Albanell, Joan; Vivancos, Ana; González, Antonio; Matito, Judit; González, Sonia; Fernandez, Pedro; Adamo, Barbara; Muñoz, Montserrat; Viladot, Margarita; Font, Carme; Aya, Francisco; Vidal, Maria; Caballero, Rosalía; Carrasco, Eva; Altomare, Vittorio; Tonini, Giuseppe; Prat, Aleix; Martin, Miguel (Impact Journals, 2017)
    PAM50/Prosigna gene expression-based assay identifies three categorical risk of relapse groups (ROR-low, ROR-intermediate and ROR-high) in post-menopausal patients with estrogen receptor estrogen receptor-positive (ER+)/ ...
  • FISH analysis of PTEN in endometrial carcinoma. Comparison with SNP arrays and MLPA 

    Maiques Carlos, Oscar; Cuevas, Dolors; García Dios, Diego Andrés; Coenegrachts, Lieve; Santacana, Maria; Velasco, Ana; Romero, Marta; Gatius Calderó, Sònia; Lambrechts, Diether; Müller, Sven; Pedersen, Hans Christian; Dolcet Roca, Xavier; Amant, Frederic; Matias-Guiu, Xavier (Wiley, 2014)
    Aims: To check the usefulness of a standardized protocol of PTEN FISH in 31 endometrial carcinomas (ECs) in comparison with SNP array (SNPA), multiplex ligation-dependent probe amplification (MLPA), and immunohistochemistry. ...
  • A Review of Clinical Studies and Practical Guide for the Administration of Triplet Chemotherapy Regimens with Bevacizumab in First-line Metastatic Colorectal Cancer 

    Loupakis, Fotios; Stein, Alexander; Ychou, Marc; Hermann, Frank; Salud Salvia, Maria Antonieta; Österlund, Pia (Springer, 2016)
    Colorectal cancer is the third most common cancer worldwide. A significant proportion of patients presents with unresectable metastatic disease or develops metachronous metastases following surgical resection of the primary ...
  • Bin-CE: A comprehensive web application to decide upon the best set of outcomes to be combined in a binary composite endpoint 

    Marsal Mora, Josep Ramon; Ferreira-González, Ignacio; Ribera, Aida; Oristrell, Gerard; Pijoan, Jose Ignacio; García-Dorado, David (Public Library of Science, 2018)
    The estimation of the Sample Size Requirement (SSR) when using a binary composite endpoint (i.e. two or more outcomes combined in a unique primary endpoint) is not trivial. Besides information about the rate of events for ...
  • Enabling Metabolomics Based Biomarker Discovery Studies Using Molecular Phenotyping of Exosome-Like Vesicles 

    Altadill, Tatiana; Campoy, Irene; Lanau, Lucia; Gill, Kirandeep; Rigau, Marina; Gil-Moreno, Antonio; Reventós, Jaume; Byers, Stephen; Colás, Eva; Cheema, Amrita K. (Public Library of Science, 2016)
    Identification of sensitive and specific biomarkers with clinical and translational utility will require smart experimental strategies that would augment expanding the breadth and depth of molecular measurements within the ...
  • Impact of an Educational Program to Reduce Healthcare Resources in CommunityAcquired Pneumonia: The EDUCAP Randomized Controlled Trial 

    Adamuz, Jordi; Viasus, Diego; Simonetti, Antonella; Jiménez-Martínez, Emilio; Molero, Lorena; González-Samartino, Maribel; Castillo, Elena; Juvé-Udina, María-Eulalia; Alcocer, María-Jesús; Hernández, Carme; Buera, María-Pilar; Roel, Asunción; Abad, Emilia; Zabalegui, Adelaida; Ricart, Pilar; Gonzalez, Anna; Isla, Pilar; Dorca, Jordi; Garcia-Vidal, Carolina; Carratalà, Jordi (Public Library of Science, 2015)
    Background: Additional healthcare visits and rehospitalizations after discharge are frequent among patients with community-acquired pneumonia (CAP) and have a major impact on healthcare costs. We aimed to determine whether ...

View more