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    Open Access
    Percepciones de matronas de Atención Primaria sobre el uso de la telemedicina durante la pandemia COVID-19 en Espana
    (Elsevier, 2023) Loezar Hernández, Mariana; Briones Vozmediano, Erica Tula; Gea Sánchez, Montserrat; Robledo Martín, Juana; Otero García, Laura
    Objetivo Explorar las experiencias de matronas/es de atención primaria de salud (APS) con la implementación de la telemedicina en la atención al embarazo y puerperio durante la pandemia por COVID-19. Método Estudio cualitativo exploratorio basado en análisis de contenido inductivo de 15 entrevistas semiestructuradas realizadas a matronas/es de APS en 2021–2022, seleccionadas intencionalmente en cuatro Comunidades Autónomas españolas. Resultados Se identificaron cinco categorías: (1) cambios en la modalidad de atención en el embarazo y puerperio: priorización de mujeres embarazadas, puerperio desprotegido, aumento de visitas domiciliarias y declive de los grupos de educación parental, (2) implementación de la telemedicina en un escenario cambiante: el lado positivo y negativo de la telemedicina (3) reacción de las mujeres ante la telemedicina (4) estrategias implementadas por las matronas para un cuidado humanizado, (5) aprendizajes para el futuro. Conclusiones El uso de la telemedicina por parte de matronas de atención primaria posibilitó la atención de mujeres embarazadas y puérperas durante la pandemia en España. Los aspectos positivos de la puesta en marcha de este tipo de atención plantean posibilidades de cambio hacia un formato híbrido de atención sanitaria.
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    Open Access
    The Spanish Adaptation of the Palliative Performance Scale (Version 2) Among Cancer Patients at the End of Life: Psychometric Properties
    (Elsevier, 2017) Barallat Gimeno, Eva; Nabal Vicuña, Maria; Canal, Jaume; Trujillano Cabello, Javier; Gea Sánchez, Montserrat; Larkin, Philip; Downing, Michael G.
    Background Palliative Performance Scale (PPS) is a reliable tool to assess performance status in cancer patients receiving palliative care (PC). Spanish validated and culturally adapted tools are needed. Objectives The objectives are to develop PPS translation and cross-cultural adaptation into Spanish and to assess its psychometric properties. Design Translation process with cross-cultural adaptation to produce Spanish Palliative Performance Scale (PPS-SPANISH). Settings PC Team at one University hospital in Spain. Participants Fifteen advanced cancer patients (60 assessments) were included for PPS translation and validation and 250 patients for cross-sectional analysis. All participants were recruited at oncology ward, emergency area, and outpatient clinic by PC team professionals. Informed consent was given. Average age was 66.4 ± 13 years (60% men). Methods The process is designed in three steps. In Step 1, PPS translation and reverse translation into Spanish (three bilingual speakers) and linguistic complexity measurement were performed. In Step 2, readability and intelligibility assessment was carried out. In Step 3, a pilot study was conducted to assess test-retest reliability followed by a cross-sectional study to measure internal consistency. Inclusion criteria were the same for two samples. Demographic data were also analyzed by descriptive statistics. Results Following cultural, linguistic, and grammatical adaptation, PPS-SPANISH was readable and reliable. The analysis of the test-retest reliability after 48 hours showed intraclass correlations >0.60. Cronbach's alpha coefficient was 0.99 (0.988–0.992). There was high agreement with other functional assessment tools (Barthel Index and Karnofsky Performance Status Index). Conclusions PPS-SPANISH showed reliability and validity, and it is suitable to assess performance status in cancer patients receiving PC.
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    Open Access
    Testing the Intermediary Role of Perceived Stress in the Relationship between Mindfulness and Burnout Subtypes in a Large Sample of Spanish University Students
    (MDPI, 2020) Martínez Rubio, David; Sanabria Mazo, Juan P.; Feliu Soler, Albert; Colomer Carbonell, Ariadna; Martínez Brotóns, Cristina; Solé Cases, Silvia; Escamilla, Cristina; Giménez Fita, Elisa; Moreno, Yolanda; Pérez Aranda, Adrián; Luciano, Juan V.; Montero Marín, Jesús
    The burnout syndrome is the consequence of chronic stress that overwhelms an individual’s resources to cope with occupational or academic demands. Frenetic, under-challenged, and worn-out are different burnout subtypes. Mindfulness has been recognized to reduce stress, comprising five facets (observing, describing, acting with awareness, non-judging of inner experience, and non-reactivity to inner experience). This cross-sectional study aimed to assess the relationship between mindfulness facets, perceived stress, and burnout subtypes in a sample of 1233 students of Education, Nursing, and Psychology degrees from different universities of Valencia (Spain). Structural Equation Modelling (SEM) was computed showing an adequate fit (Chi-square, CFI, TLI, RMSEA, and SRMR). Four mindfulness facets (all but observing) significantly correlated with general second-order mindfulness. Unexpected results were found: Acting with awareness facet was positively associated with frenetic subtype, while the non-reacting facet was positively associated with frenetic and under-challenged subtype. Ultimately, mindfulness facets negatively predicted the perceived stress levels, which in turn, predicted burnout. However, mindfulness plays different roles in the early stages of burnout syndrome (i.e., frenetic and under-challenged).
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    Open Access
    Adolescència en creixement: actualització dels actius interns i externs del desenvolupament positiu adolescent
    (Edicions de la Universitat de Lleida, 2023) Balsells, M. Àngels; Urrea Monclús, Aida; Fernández Rodrigo, Laura; Forné Samitier, Maria Alba; Simó Cunillera, Íngrid
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    Open Access
    Correction to: Type 2 diabetes-associated carotid plaque burden is increased in patients with retinopathy compared to those without retinopathy
    (BioMed Central, 2018) Alonso, Núria; Traveset Maeso, Alicia; Rubinat, Esther; Ortega, Emilio; Alcubierre Calvo, Núria; Sanahuja Montesinos, Jordi; Hernández García, Marta; Betriu i Bars, M. Àngels; Jurjo Campo, Carmen; Fernández i Giráldez, Elvira; Mauricio Puente, Dídac
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    Open Access
    Protocol to characterize the melanoma tumor immune microenvironment in mice from single cell to flow cytometry analysis
    (Cell Press, 2023-12-15) Sisó, Pol; de la Rosa, Inés; Ríos, Christopher; Panosa, Anais; Verdaguer Autonell, Joan; Martí Laborda, Rosa Ma; Macià Armengol, Anna
    Here, we present a protocol to study and describe immune cells that surround or infiltrate tumor cells or get through the body of a melanoma syngeneic mice model. We describe steps for creating and establishing the syngeneic mouse model, euthanasia, and tumor or organ harvest. We then detail procedures to rapidly achieve a single-cell suspension from different tissue samples to further quantify and analyze the phenotype of the immune cell population (lymphocytes T and B, tumor-associated macrophages, and myeloid-derived suppressor cells) by flow cytometry.
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    Open Access
    Protein turnover in pigs: A review of interacting factors
    (Wiley, 2023-11-17) Sarri Espinosa, Laura; Balcells Terés, Joaquim; Seradj, Ahmad Reza; de la Fuente Oliver, Gabriel
    Protein turnover defines the balance between two continuous and complex processes of protein metabolism, synthesis and degradation, which determine their deposition in tissues. Although the liver and intestine have been studied extensively for their important roles in protein digestion, absorption and metabolism, the study of protein metabolism has focused mainly on skeletal muscle tissue to understand the basis for its growth. Due to the high adaptability of skeletal muscle, its protein turnover is greatly affected by different internal and external factors, contributing to carcass lean‐yield and animal growth. Amino acid (AA) labelling and tracking using isotope tracer methodology, together with the study of myofiber type profiling, signal transduction pathways and gene expression, has allowed the analysis of these mechanisms from different perspectives. Positive stimuli such as increased nutrient availability in the diet (e.g., AA), physical activity, the presence of certain hormones (e.g., testosterone) or a more oxidative myofiber profile in certain muscles or pig genotypes promote increased upregulation of translation and transcription‐related genes, activation of mTORC1 signalling mechanisms and increased abundance of satellite cells, allowing for more efficient protein synthesis. However, fasting, animal aging, inactivity and stress, inflammation or sepsis produce the opposite effect. Deepening the understanding of modifying factors and their possible interaction may contribute to the design of optimal strategies to better control tissue growth and nutrient use (i.e., protein and AA), and thus advance the precision feeding strategy.
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    Open Access
    Prefazione. La Sardegna e Giovanni I nel rinnovamento storiografico della Corona d'Aragona
    (Consiglio Nacionale delle Richerche Istituto di Storia dell' Europa Mediterranea CNR - ISEM, 2013) Sabaté, Flocel
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    Open Access
    TAN-IBE: Neural Machine Translation for the Romance Languages of the Iberian Peninsula
    (CEUR Workshop Proceedings, 2023) Oliver, Antoni; Vàzquez, Mercè; Coll-Florit, Marta; Álvarez, Sergi; Suárez, Víctor; Aventín-Boya, Claudi; Valdés, Cristina; Font Martí, Mar; Pardos, Alejandro
    This paper describes the project TAN-IBE: Neural Machine Translation for the Romance Languages of the Iberian Peninsula, a three-year research project. Its main objective is to conduct research on techniques for training NMT systems for these languages, as there are high, medium and low resource languages among them. Particular attention will be paid to the languages with fewer resources: Asturian, Aragonese and Aranese.
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    Open Access
    Mass animal sacrifice at casas del Turuñuelo (Guareña, Spain): A unique Tartessian (Iron Age) site in the southwest of the Iberian Peninsula
    (Public Library of Science, 2023-11-22) Iborra Eres, Maria Pilar; Albizuri, Silvia; Gutiérrez Rodríguez, Mario; Jiménez Fragoso, Joaquín; Lira Garrido, Jaime; Martín Cuervo, María; Martínez Sánchez, Rafael María; Martínez Valle, Rafael; Mayoral, Ana Isabel; Nieto Espinet, Ariadna; Rodríguez González, Esther; Valenzuela-Lamas, Silvia; Celestino Pérez, Sebastián
    Zooarchaeological analyses of the skeletal remains of 52 animals unearthed in the courtyard of an Iron Age Tartessian building known as Casas del Turuñuelo (Badajoz, Spain) shed light on a massive sacrifice forming part of a series of rituals linked to the site’s last period of activity and final abandonment. The rites took place towards the end of the 5th century BCE when both the building (intentionally destroyed) and the sacrificed animals were intentionally buried under a tumulus 90 m in diameter and 6 m high. The main objective of the zooarchaeological and microstratigraphic analyses was to determine the phasing of the sacrificial depositions. Evidence gathered from taphonomic assessments and a series of radiocarbon datings indicate that the sacrifices fall into three consecutive phases spanning several years. The findings of the zooarchaeological analyses clearly point to a selection of equid and cattle males. Adult equids predominate (MNI = 41) followed by adult and sub-adult cattle (MNI = 6). Pigs, in turn, are only represented by a few adults and sub-adult females (MNI = 4). Among the animals is a single dog of undetermined sex between 3 and 4 years of age. The fact that the animals are mostly adults discards the likelihood that they died from natural causes or an epidemic. In addition, the scenographic deposition of certain equids in pairs, as well as evidence of the burning of plant offerings, suggest an intentional ritualistic sacrifice. Nine of the initial depositions of Phase 1 in the SE quadrant were scattered and certain of their bones bear marks characteristic of both prolonged open air exposure and scavengers. Another 31 animals from Phases 1 and 2 are represented by almost complete, articulated skeletons, indicating they were promptly covered. Phase 3, by contrast, reveals both almost complete and partial animals bearing clear signs of processing for human consumption. This study thus sheds light on both the sequence of the animal sacrifices and the protocols linked to rites accompanied by the celebration of banquets. Certain features associated with the sealing of this building under a tumulus offer evidence of the decline of the Tartessian Culture. This study thus advances notions serving to contextualize ritual animal sacrifices in the framework of practice observed at other Iron Age sites in the Iberian Peninsula and elsewhere throughout Europe.