Factors predicting failure of endoscopic injection therapy in bleeding duodenal ulcer

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dc.contributor.authorBrullet, Enric
dc.contributor.authorCalvet, Xavier
dc.contributor.authorCampo, Rafel
dc.contributor.authorRué i Monné, Montserrat
dc.contributor.authorCatot, Llúcia
dc.contributor.authorDonoso, Lluis
dc.date.accessioned2016-05-03T09:41:38Z
dc.date.embargoEndDate2025-01-01
dc.date.issued1996
dc.description.abstractBackground: The aim of this study was to assess the factors that may cause failure of endoscopic injection in patients bleeding from a duodenal ulcer. Methods: One hundred twenty patients admitted for a bleeding duodenal ulcer with active arterial hemorrhage or a nonbleeding visible vessel were included. Results: Endoscopic injection was not feasible in 14 of 120 (11.6%) patients because of inaccessibility or massive hemorrhage. The remaining 106 patients underwent endoscopic therapy by injection of adrenaline and polidocanol. The efficacy (achievement of definitive hemostasis) of endoscopy therapy was 83% (88 of 106). Univariate analysis showed that failure of endoscopic injection was related to age, presence of shock, ulcer size greater than 2 cm, and hemoglobin level. Multivariate analysis showed that ulcer size greater than 2 cm (p = 0.005) and the presence of shock (p = 0.03) were factors predictive of endoscopic treatment failure. Failure to achieve hemostasis (p < 0.001) and poor physical status measured by American Society of Anesthesiology classification (p = 0.02) were significantly related to mortality. Conclusions: Ulcer size and severity of hemorrhage are predictive of endoscopic injection failure in patients bleeding from high-risk duodenal ulcers. Survival is determined by clinical status and associated diseases. (Gastrointest Endosc 1996;43:111-6.)ca_ES
dc.identifier.doihttps://doi.org/10.1016/S0016-5107(06)80110-0
dc.identifier.idgrec010470
dc.identifier.issn0016-5107
dc.identifier.urihttp://hdl.handle.net/10459.1/56936
dc.language.isoengca_ES
dc.publisherElsevierca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1016/S0016-5107(06)80110-0ca_ES
dc.relation.ispartofGastrointestinal Endoscopy, 1996, vol. 43, núm. 2(1), p. 111-116ca_ES
dc.rights(c) American Society for Gastrointestinal Endoscopy, 1996ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_ES
dc.titleFactors predicting failure of endoscopic injection therapy in bleeding duodenal ulcerca_ES
dc.typearticleca_ES
dc.type.versionpublishedVersionca_ES
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