From single to multiresponse modelling of food digestion kinetics: The case of lipid digestion

dc.contributor.authorVerkempinck, S.H.E.
dc.contributor.authorSalvia Trujillo, Laura
dc.contributor.authorInfantes Garcia, M.R.
dc.contributor.authorHendrickx, M.E.
dc.contributor.authorGrauwet, Tara
dc.date.accessioned2022-02-23T09:59:44Z
dc.date.available2022-02-23T09:59:44Z
dc.date.issued2019
dc.description.abstractThis work presents that lipid digestion kinetics of oil-in-water emulsions can be described by a mechanism-based multiresponse model. The modelling approach proposed takes into account multiple interlinked responses of in vitro lipolysis. Different reaction schemes are proposed and iteratively adapted for one dataset. Based on model discrimination, the model that best described the experimental data was selected. This selected multiresponse model assumes that 1 mol triacylglycerol hydrolyzes to release either 1 mol of monoacylglycerol and 2 mol of free fatty acids or either 3 mol of free fatty acids and 1 mol glycerol. Convergence was evaluated, as well as goodness of fit and accuracy of the parameter estimates (R2adj>0.986). The validity of this mechanistic model was checked using 28 independent datasets and clearly surpasses the outcome of single response modelling. This is the first proof of concept of the potential of multiresponse modelling in the context of food digestion.ca_ES
dc.identifier.doihttps://doi.org/10.1016/j.jfoodeng.2019.04.018
dc.identifier.idgrec029596
dc.identifier.issn0260-8774
dc.identifier.urihttp://hdl.handle.net/10459.1/73063
dc.language.isoengca_ES
dc.publisherElsevierca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1016/j.jfoodeng.2019.04.018ca_ES
dc.relation.ispartofJournal of Food Engineering, 2019, vol. 260, p. 40-49ca_ES
dc.rightscc-by-nc-nd (c) Elsevier, 2019ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectLipid digestionca_ES
dc.subjectMultiresponse modellingca_ES
dc.subjectReaction mechanismca_ES
dc.subjectIn vitro digestionca_ES
dc.subject.otherLípids en la nutricióca_ES
dc.subject.otherDigestióca_ES
dc.subject.otherKineticsca_ES
dc.titleFrom single to multiresponse modelling of food digestion kinetics: The case of lipid digestionca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.type.versioninfo:eu-repo/semantics/acceptedVersionca_ES
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