Energetic metabolism in fasting sheep: regularization of metabolic profile by treatment with oral glucose, with prior handling of gastric groove

dc.contributor.authorMartín-Alonso, María José
dc.contributor.authorEscalera-Valente, Francisco
dc.contributor.authorCal-Pereyra, Luis G.
dc.contributor.authorBenech, Alejandro
dc.contributor.authorAlonso Alonso, María del Pilar
dc.contributor.authorGonzález Montaña, José Ramiro
dc.date.accessioned2020-01-21T11:20:26Z
dc.date.available2020-01-21T11:20:26Z
dc.date.issued2019-11-28
dc.description.abstractThe objective of this research was to evaluate a possible corrective measure against negative metabolic states, as occurs in the advanced stage of gestation in ewes, and that sometimes produces a disease called pregnancy toxaemia. In the present research, we found that the joint administration of i.v. lysine-vasopressin (0.08 IU/kg body weight, BW) and an oral glucose solution (50 g) produces an increase in blood glucose, which persists for some time (up to 6 h); therefore, it could be used in the treatment of pregnancy toxaemia. This therapy is based on the fact that lysine-vasopressin induces gastric groove closure in adult ruminants, enabling orally administered glucose to reach the abomasum directly, from where it rapidly passes into the intestine and is immediately absorbed. We can say that the tested treatment causes a significant increase in blood glucose in ewes affected by toxaemia caused by fasting, which, although less marked than conventional therapy with intravenous drip glucose, remains longer, regularizing other parameters indicative of energy metabolism in fasting ewes.ca_ES
dc.identifier.doihttps://doi.org/10.1590/rbz4820180290
dc.identifier.idgrec031662
dc.identifier.issn1516-3598
dc.identifier.urihttp://hdl.handle.net/10459.1/67833
dc.language.isoengca_ES
dc.publisherUniversidade Federal de Viçosaca_ES
dc.relation.isformatofReproducció del document publicat a: http://dx.doi.org/10.1590/rbz4820180290ca_ES
dc.relation.ispartofRevista Brasileira de Zootecnia, 2019, vol.48, e20180290ca_ES
dc.rightscc-by (c) Martín-Alonso, María José et al., 2019ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectEwesca_ES
dc.subjectGastric grooveca_ES
dc.subjectGlycaemiaca_ES
dc.subjectMetabolismca_ES
dc.subjectPregnancyca_ES
dc.subjectToxaemiaca_ES
dc.subjectVasopressinca_ES
dc.titleEnergetic metabolism in fasting sheep: regularization of metabolic profile by treatment with oral glucose, with prior handling of gastric grooveca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
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