European survey on preanalytical sample handling – Part 2: Practices of European laboratories on monitoring and processing haemolytic, icteric and lipemic samples. On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)

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dc.contributor.authorCadamuro, Janne
dc.contributor.authorLippi, Giuseppe
dc.contributor.authorvon Meyer, Alexander
dc.contributor.authorIbarz Escuer, Mercedes
dc.contributor.authorvan Dongen–Lases, Edmee
dc.contributor.authorCornes, Michael
dc.contributor.authorNybo, Mads
dc.contributor.authorVermeersch, Pieter
dc.contributor.authorGrankvist, Kjell
dc.contributor.authorGuimaraes, Joao Tiago
dc.contributor.authorKristensen, Gunn B.
dc.contributor.authorde la Salle, Barbara
dc.contributor.authorSimundic, Ana-Maria
dc.date.accessioned2020-05-29T07:59:17Z
dc.date.available2020-05-29T07:59:17Z
dc.date.issued2019
dc.description.abstractIntroduction: No guideline currently exists on how to detect or document haemolysis, icterus or lipemia (HIL) in blood samples, nor on subsequent use of this information. The EFLM WG-PRE has performed a survey for assessing current practices of European laboratories in HIL monitoring. This second part of two coherent articles is focused on HIL. Materials and methods: An online survey, containing 39 questions on preanalytical issues, was disseminated among EFLM member countries. Seventeen questions exclusively focused on assessment, management and follow-up actions of HIL in routine blood samples. Results: Overall, 1405 valid responses from 37 countries were received. A total of 1160 (86%) of all responders stating to analyse blood samples - monitored HIL. HIL was mostly checked in clinical chemistry samples and less frequently in those received for coagulation, therapeutic drug monitoring and serology/infectious disease testing. HIL detection by automatic HIL indices or visual inspection, along with haemolysis cut-offs definition, varied widely among responders. A quarter of responders performing automated HIL checks used internal quality controls. In haemolytic/icteric/lipemic samples, most responders (70%) only rejected HIL-sensitive parameters, whilst about 20% released all test results with general comments. Other responders did not analysed but rejected the entire sample, while some released all tests, without comments. Overall, 26% responders who monitored HIL were using this information for monitoring phlebotomy or sample transport quality. Conclusion: Strategies for monitoring and treating haemolytic, icteric or lipemic samples are quite heterogeneous in Europe. The WG-PRE will use these insights for developing and providing recommendations aimed at harmonizing strategies across Europe.ca_ES
dc.identifier.doihttps://doi.org/10.11613/BM.2019.020705
dc.identifier.idgrec028828
dc.identifier.issn1330-0962
dc.identifier.issn1846-7482 (Online)
dc.identifier.urihttp://hdl.handle.net/10459.1/68865
dc.language.isoengca_ES
dc.publisherCroatian Society of Medical Biochemistry and Laboratory Medicineca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.11613/BM.2019.020705ca_ES
dc.relation.ispartofBiochemia Medica, 2019, vol. 29, núm. 2ca_ES
dc.rightscc-by, (c) Croatian Society of Medical Biochemistry, 2018ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPreanalyticsca_ES
dc.subjectStandardizationca_ES
dc.subjectSurveyca_ES
dc.titleEuropean survey on preanalytical sample handling – Part 2: Practices of European laboratories on monitoring and processing haemolytic, icteric and lipemic samples. On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE)ca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
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