Polyphenol Intake in Pregnant Women on Gestational Diabetes Risk and Neurodevelopmental Disorders in Offspring: A Systematic Review

dc.contributor.authorSalinas-Roca, Blanca
dc.contributor.authorRubió Piqué, Laura
dc.contributor.authorMontull-López, Anna
dc.date.accessioned2022-11-27T14:28:13Z
dc.date.available2022-11-27T14:28:13Z
dc.date.issued2022
dc.description.abstractThe intake of foods containing polyphenols can have a protective role to avoid comorbidities during pregnancy and, at the same time, promote transgenerational health. This review aims to describe the effect of polyphenol intake through supplements or polyphenol-rich foods during pregnancy on the incidence and evolution of gestational diabetes mellitus (GDM), as well as the link with the neurodevelopment of the fetus. Using PRISMA procedures, a systematic review was conducted by searching in biomedical databases (PubMed, Cinahl and Scopus) from January to June 2022. Full articles were screened (n = 419) and critically appraised. Fourteen studies were selected and were divided into two different thematic blocks considering (i) the effect of polyphenols in GDM and (ii) the effect of GDM to mental disorders in the offspring. A positive relationship was observed between the intake of polyphenols and the prevention and control of cardiometabolic complications during pregnancy, such as GDM, which could be related to thwarted inflammatory and oxidative processes, as well as neuronal factors. GDM is related to a greater risk of suffering from diseases related to neurodevelopment, such as attention deficit hyperactivity disorder, autism spectrum disorder and learning disorder. Further clinical research on the molecule protective mechanism of polyphenols on pregnant women is required to understand the transgenerational impact on fetal neurodevelopment.ca_ES
dc.identifier.doihttps://doi.org/10.3390/nu14183753
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/10459.1/84376
dc.language.isoengca_ES
dc.publisherMDPIca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.3390/nu14183753ca_ES
dc.relation.ispartofNutrients, 2022, vol. 14, núm. 18, art. 3753.ca_ES
dc.rightscc-by (c) Blanca Salinas-Roca et al., 2022ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPregnant womenca_ES
dc.subjectPolyphenolca_ES
dc.subjectGestational diabetesca_ES
dc.subjectFetal neurodevelopmentca_ES
dc.subjectTransgenerational healthca_ES
dc.titlePolyphenol Intake in Pregnant Women on Gestational Diabetes Risk and Neurodevelopmental Disorders in Offspring: A Systematic Reviewca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
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