Characterization of the CPAP-treated patient population in Catalonia

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dc.contributor.authorTurino, Cecilia
dc.contributor.authorBertran, Sandra
dc.contributor.authorGavaldá, Ricard
dc.contributor.authorTeixidó Torrelles, Ivan
dc.contributor.authorWoehrle, Holger
dc.contributor.authorRué i Monné, Montserrat
dc.contributor.authorSolsona Tehàs, Francesc
dc.contributor.authorEscarrabill, Joan
dc.contributor.authorColls, Cristina
dc.contributor.authorGarcía-Altés, Anna
dc.contributor.authorBatlle Garcia, Jordi de
dc.contributor.authorSánchez de la Torre, Manuel
dc.contributor.authorBarbé Illa, Ferran
dc.date.accessioned2017-10-26T08:50:17Z
dc.date.available2017-10-26T08:50:17Z
dc.date.issued2017
dc.description.abstractThere are different phenotypes of obstructive sleep apnoea (OSA), many of which have not been characterised. Identification of these different phenotypes is important in defining prognosis and guiding the therapeutic strategy. The aim of this study was to characterise the entire population of continuous positive airway pressure (CPAP)-treated patients in Catalonia and identify specific patient profiles using cluster analysis. A total of 72,217 CPAP-treated patients who contacted the Catalan Health System (CatSalut) during the years 2012 and 2013 were included. Six clusters were identified, classified as “Neoplastic patients” (Cluster 1, 10.4%), “Metabolic syndrome patients” (Cluster 2, 27.7%), “Asthmatic patients” (Cluster 3, 5.8%), “Musculoskeletal and joint disorder patients” (Cluster 4, 10.3%), “Patients with few comorbidities” (Cluster 5, 35.6%) and “Oldest and cardiac disease patients” (Cluster 6, 10.2%). Healthcare facility use and mortality were highest in patients from Cluster 1 and 6. Conversely, patients in Clusters 2 and 4 had low morbidity, mortality and healthcare resource use. Our findings highlight the heterogeneity of CPAP-treated patients, and suggest that OSA is associated with a different prognosis in the clusters identified. These results suggest the need for a comprehensive and individualised approach to CPAP treatment of OSA.ca_ES
dc.description.sponsorshipThis study was supported by the Spanish Respiratory Society (SEPAR), Associació Lleidatana de Respiratori (ALLER) and ResMed, a company that provides diagnostic services and treatment for sleep apnoea.ca_ES
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0185191
dc.identifier.idgrec026051
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/10459.1/60370
dc.language.isoengca_ES
dc.publisherPublic Library of Scienceca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1371/journal.pone.0185191ca_ES
dc.relation.ispartofPlos One, 2017, vol. 12, núm. 9, p. 1-12ca_ES
dc.rightscc-by (c) Turino et al., 2017ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleCharacterization of the CPAP-treated patient population in Cataloniaca_ES
dc.typearticleca_ES
dc.type.versionpublishedVersionca_ES
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