Epidemiological and clinical characteristics of SARS-CoV-2 reinfections in a Spanish region

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Yuguero Torres, OriolYuguero Torres, Oriol - ORCID ID
Companys, Maria
Guzmán, Marianela
Maciel, Rita
Llobet, Cecilia
López, Aurora
Olles, Rebeca
Pujol, Violant
Ruiz Montilla, María José
Saura, Mireia
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cc-by-nc (c) Oriol Yuguero et. al., 2022.
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Objective: We aimed to assess the prevalence and clinical characteristics of SARS-CoV-2 reinfections in a Spanish region. Methods: This is a retrospective observational study in all patients with SARS-CoV-2 infections in the Lleida health region from 1 March to 30 November 2020. Reinfections were classified as patients with positive SARS-CoV-2 PCR tests separated by at least 90days plus a negative test result between both infection episodes. Primary and secondary outcomes: The primary outcome was the percentage of SARS-CoV-2 reinfections among all SARS-CoV-2 infections detected during our study period. Secondary outcomes were the clinical and sociodemographic characteristics of patients with SARS-CoV-2 reinfections. Results: Of the 27,758 patients diagnosed with SARS-CoV-2 infection in the study period, 14 were identified as coronavirus reinfection (0.050%). Of the reinfected sample, 12 patients (85.7%) were women. The median age was 41.5 years. Two patients died in the second coronavirus episode. Conclusion: The reinfection rate of SARS-CoV-2 in the Spanish region Lleida was relatively low during the observational period in 2020 (less than 1%). These data are in line with the notion that previous SARS-CoV-2 infections may offer a significant protection by so called natural immunity.
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SAGE Open Medicine, 2022, vol. 10, p. 1-6.