Long lifespans have evolved with long and monounsaturated fatty acids in birds

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dc.contributor.authorGalván, Ismael
dc.contributor.authorNaudí i Farré, Alba
dc.contributor.authorErritzøe, Johannes
dc.contributor.authorMøller, Anders P.
dc.contributor.authorBarja, Gustavo
dc.contributor.authorPamplona Gras, Reinald
dc.date.accessioned2018-11-07T10:40:57Z
dc.date.available2018-11-07T10:40:57Z
dc.date.issued2015
dc.description.abstractThe evolution of lifespan is a central question in evolutionary biology, begging the question why there is so large variation among taxa. Specifically, a central quest is to unravel proximate causes of ageing. Here, we show that the degree of unsaturation of liver fatty acids predicts maximum lifespan in 107 bird species. In these birds, the degree of fatty acid unsaturation is positively related to maximum lifespan across species. This is due to a positive effect of monounsaturated fatty acid content, while polyunsaturated fatty acid content negatively correlates with maximum lifespan. Furthermore, fatty acid chain length unsuspectedly increases with maximum lifespan independently of degree of unsaturation. These findings tune theories on the proximate causes of ageing while providing evidence that the evolution of lifespan in birds occurs in association with fatty acid profiles. This suggests that studies of proximate and ultimate questions may facilitate our understanding of these central evolutionary questions.ca_ES
dc.description.sponsorshipWe acknowledge funding from the Spanish Ministry of Economy and Competitiveness (references BFU2009‐11879/BFI, RD12/0043/0018, PI1300584, and PI1400328), and the Autonomous Government of Catalonia (ref. 2014SGR168) to R.P. I.G. is supported by a Ramón y Cajal Fellowship (ref. RYC‐2012‐10237) from the Spanish Ministry of Economy and Competitiveness.ca_ES
dc.identifier.doihttps://doi.org/10.1111/evo.12754
dc.identifier.idgrec023679
dc.identifier.issn0014-3820
dc.identifier.urihttp://hdl.handle.net/10459.1/65043
dc.language.isoengca_ES
dc.publisherSociety for the Study of Evolutionca_ES
dc.publisherWiley
dc.relationinfo:eu-repo/grantAgreement/MICINN//BFU2009-11879/ES/Efecto Del Envejecimiento Y De La Restriccion De Metionina Sobre La Vulnerabilidad Neuronal Al Estres Oxidativo En Diferentes Regiones Del Sistema Nervioso Central/
dc.relation.isformatofVersió postprint del document publicat a https://doi.org/10.1111/evo.12754ca_ES
dc.relation.ispartofEvolution, 2015, vol. 69, núm. 10, p. 2776-2784ca_ES
dc.rights(c) Society for the Study of Evolution, 2015ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.subjectAgeingca_ES
dc.subjectBirdsca_ES
dc.subjectHomeoviscous longevity adaptation hypothesisca_ES
dc.subjectLongevityca_ES
dc.titleLong lifespans have evolved with long and monounsaturated fatty acids in birdsca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.type.versioninfo:eu-repo/semantics/acceptedVersionca_ES
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