Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study.

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dc.contributor.authorPodlipnik, Sebastian
dc.contributor.authorCarrera, Cristina
dc.contributor.authorBoada, Aram
dc.contributor.authorRicharz, Nina
dc.contributor.authorMarcoval, Joaquim
dc.contributor.authorFerreres, Josep Ramón
dc.contributor.authorBodet, Domingo
dc.contributor.authorMartí Laborda, Rosa Ma.
dc.contributor.authorSegura, Sonia
dc.contributor.authorSabat, Mireia
dc.contributor.authorDalmau, Joan
dc.contributor.authorQuintana, Mònica
dc.contributor.authorAzon, Antoni
dc.contributor.authorCurcó, Neus
dc.contributor.authorFormigon, Manel
dc.contributor.authorOlivella-Garcés, María Rosa
dc.contributor.authorZaballos, Pedro
dc.contributor.authorSola, Joaquim
dc.contributor.authorGalvany, Loida
dc.contributor.authorBaliu-Piqué, Carola
dc.contributor.authorAlegre, Marta
dc.contributor.authorPasquali, Paola
dc.contributor.authorMalvehy, Josep
dc.contributor.authorPuig, Susana
dc.contributor.otherNetwork of Melanoma Centres of Catalonia
dc.date.accessioned2020-12-28T13:47:48Z
dc.date.available2020-12-28T13:47:48Z
dc.date.issued2020
dc.date.updated2020-12-28T13:47:48Z
dc.description.abstractThe incidence of melanoma has been increasing worldwide during recent decades. The objective of the study was to analyse the trends in incidence for in situ and invasive melanoma in the Spanish region of Catalonia during the period of 2008-2017. We designed a cross-sectional study with an age-period-cohort analysis of melanoma patient data from the Network of Melanoma Centres in Catalonia. Our database covered a population of over seven million and included a total of 8626 patients with incident melanoma. The main outcome measures were crude and age-standardised incidence rates to the European 2013 standard population. Joinpoint regression models were used to evaluate the population trends. We observed an increase in the age-standardised incidence rate (per 100,000 population) of all melanoma subtypes from 11.56 in 2008 to 13.78 in 2017 with an average annual percent change (AAPC) of 3.5%. This incidence increase was seen exclusively in the older population. Moreover, the stratified analysis showed a statistically significant increase in the age-standardised incidence rate for invasive (AAPC 2.1%) and in situ melanoma (AAPC 6.5%). In conclusion, the incidence of melanoma has continued to increase in the elderly population over recent decades, with a rapidly increasing trend of in situ melanomas and the lentigo maligna subtype.
dc.description.sponsorshipThe study in the Melanoma Unit, Hospital Clínic, Barcelona was supported in part by grants from Fondo de Investigaciones Sanitarias P.I. 12/00840, PI 15/00956, and PI 15/00716 Spain; by the CIBER de Enfermedades Raras of the Instituto de Salud Carlos III, Spain, co-funded by “Fondo Europeo de Desarrollo Regional (FEDER). Unión Europea. Una manera de hacer Europa”; by the AGAUR 2014_SGR_603 and 017_SGR_1134 of the Catalan Government, Spain; by a grant from “Fundació La Marató de TV3, 201331-30”, Catalonia, Spain; by the European Commission under the 6th Framework Programme, Contract no : LSHC-CT-2006-018702 (GenoMEL); by CERCA Programme/Generalitat de Catalunya; by a Research Grant from “Fundación Científica de la Asociación Española Contra el Cáncer” GCB15152978SOEN, Spain; by a grant from the European Academy of Dermatology and Venereology (EADV) (PPRC-2017/19). Part of the work was developed at the building Centro Esther Koplowitz. Melanoma research at the Department of Dermatology of Hospital Universitari Arnau de Vilanova de Lleida is supported by grants from ISCIII (PI15/00711 to RMM, cofinanced by FEDER “Una manera de hacer Europa” and CIBERONC- CB16/12/00231) and from Fundació la Marató de TV3 (FMTV 201331-31 to RMM).
dc.format.mimetypeapplication/pdf
dc.identifier.doihttps://doi.org/10.3390/jcm9113396
dc.identifier.idgrec030693
dc.identifier.issn2077-0383
dc.identifier.urihttp://hdl.handle.net/10459.1/70149
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.3390/jcm9113396
dc.relation.ispartofJournal of Clinical Medicine, 2020, vol. 9, núm. 11, p. 3396
dc.rightscc-by (c) Podlipnik, Sebastian et al., 2020
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectMelanoma
dc.subjectIncidence
dc.subjectPopulation-based study
dc.subjectEpidemiology
dc.subjectSpain
dc.subjectSkin cancer
dc.titleIncidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study.
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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