Iodine deficiency is higher in morbid obesity in comparison with late after bariatric surgery and non-obese women

dc.contributor.authorLecube Torelló, Albert
dc.contributor.authorZafon, Carles
dc.contributor.authorGromaz, Adoración
dc.contributor.authorFort, José Manuel
dc.contributor.authorCaubet, Enric
dc.contributor.authorBaena-Fustegueras, Juan A
dc.contributor.authorTortosa, Frederic
dc.date.accessioned2017-01-24T12:45:56Z
dc.date.embargoEndDate2025-01-01
dc.date.issued2015
dc.description.abstractBackground Iodine deficiency and obesity are worldwideoccurring health problems. Our purpose was to investigate the relationship between morbid obesity and iodine status, including subjects who lost weight after bariatric surgery. Methods Ninety morbidly obese women, 90 women with at least 18 months follow-up after bariatric surgery, and 45 healthy non-obese women were recruited. Urinary iodine concentration (UIC) was measured in a spot urinary sample and expressed as the iodine-to-creatinine ratio. Results Obese women showed a significantly lower UIC in comparison with non-obese women (96.6 (25.8–267.3) vs. 173.3 (47.0–493.6) μg/g; p<0.001), with a lesser proportion of subjects with adequate iodine status (46.6 vs. 83.3 %, p<0.001). The mean UIC significantly increased among women who underwent bariatric surgery before the collection of the urinary sample (96.6 (25.8–267.3) vs. 131.9 (62.9– 496.4) μg/g; p<0.001). No difference in UIC was detected between laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy. Univariate analysis showed that UIC negatively correlated with body mass index (BMI) (r=−0.278, p<0.001) and positively with age (r=0.206, p=0.002). Finally, multiple linear regression analyses showed that BMI was independently associated with UIC (beta=−0.312, p<0.001; R2=0.166). Conclusion Obesity is an independent risk factor to iodine deficiency, almost in women.Whether more obese population needs to be considered as a vulnerable group and whether bariatric surgery can reverse iodine deficiency still remain to be elucidated.ca_ES
dc.description.sponsorshipThis study was supported by a grant from the Societat Catalana d’Endocrinologia i Nutrició (SCEN).ca_ES
dc.identifier.doihttps://doi.org/10.1007/s11695-014-1313-z
dc.identifier.idgrec023962
dc.identifier.issn0960-8923
dc.identifier.urihttp://hdl.handle.net/10459.1/59091
dc.language.isoengca_ES
dc.publisherSpringer USca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1007/s11695-014-1313-zca_ES
dc.relation.ispartofObesity Surgery, 2015, vol. 25, núm. 1, p. 85–89ca_ES
dc.rights(C) Springer Science+Business Media New York, 2014ca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_ES
dc.subjectIodineca_ES
dc.subjectObesityca_ES
dc.subjectSurgeryca_ES
dc.titleIodine deficiency is higher in morbid obesity in comparison with late after bariatric surgery and non-obese womenca_ES
dc.typearticleca_ES
dc.type.versionpublishedVersionca_ES
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