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dc.contributor.authorMontoro, Miguel
dc.contributor.authorCucala-Ramos, Mercedes
dc.contributor.authorLanas, Ángel
dc.contributor.authorVillanueva, Cándido
dc.contributor.authorHervás, Antonio José
dc.contributor.authorAlcedo, Javier
dc.contributor.authorGisbert, Javier P.
dc.contributor.authorAisa, Ángeles P.
dc.contributor.authorBujanda, Luis
dc.contributor.authorCalvet, Xavier
dc.contributor.authorMearin, Fermín
dc.contributor.authorMurcia, Óscar
dc.contributor.authorCanelles, Pilar
dc.contributor.authorGarcía López, Santiago
dc.contributor.authorde Argila, Carlos Martín
dc.contributor.authorQuintana, Manuel
dc.contributor.authorJericó, Carlos
dc.contributor.authorGarcía Erce, José Antonio
dc.contributor.authorPlanella de Rubinat, Montse
dc.date.accessioned2022-11-24T08:24:37Z
dc.date.available2022-11-24T08:24:37Z
dc.date.issued2022
dc.identifier.issn2296-858X
dc.identifier.urihttp://hdl.handle.net/10459.1/84317
dc.description.abstractGastrointestinal (GI) bleeding is associated with considerable morbidity and mortality. Red blood cell (RBC) transfusion has long been the cornerstone of treatment for anemia due to GI bleeding. However, blood is not devoid of potential adverse effects, and it is also a precious resource, with limited supplies in blood banks. Nowadays, all patients should benefit from a patient blood management (PBM) program that aims to minimize blood loss, optimize hematopoiesis (mainly by using iron replacement therapy), maximize tolerance of anemia, and avoid unnecessary transfusions. Integration of PBM into healthcare management reduces patient mortality and morbidity and supports a restrictive RBC transfusion approach by reducing transfusion rates. The European Commission has outlined strategies to support hospitals with the implementation of PBM, but it is vital that these initiatives are translated into clinical practice. To help optimize management of anemia and iron deficiency in adults with acute or chronic GI bleeding, we developed a protocol under the auspices of the Spanish Association of Gastroenterology, in collaboration with healthcare professionals from 16 hospitals across Spain, including expert advice from different specialties involved in PBM strategies, such as internal medicine physicians, intensive care specialists, and hematologists. Recommendations include how to identify patients who have anemia (or iron deficiency) requiring oral/intravenous iron replacement therapy and/or RBC transfusion (using a restrictive approach to transfusion), and transfusing RBC units 1 unit at a time, with assessment of patients after each given unit (i.e., “don’t give two without review”). The advantages and limitations of oral versus intravenous iron and guidance on the safe and effective use of intravenous iron are also described. Implementation of a PBM strategy and clinical decision-making support, including early treatment of anemia with iron supplementation in patients with GI bleeding, may improve patient outcomes and lower hospital costs.ca_ES
dc.language.isoengca_ES
dc.publisherFrontiers Mediaca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.3389/fmed.2022.903739ca_ES
dc.relation.ispartofFrontiers in Medicine, 2022, vol. 9, art. 903739.ca_ES
dc.rightscc-by (c) Miguel Montoro et. al., 2022.ca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAnemiaca_ES
dc.subjectFerric carboxymaltose (FCM)ca_ES
dc.subjectGastrointestinal bleedingca_ES
dc.subjectIron supplementationca_ES
dc.subjectPatient blood managementca_ES
dc.titleIndications and hemoglobin thresholds for red blood cell transfusion and iron replacement in adults with gastrointestinal bleeding: An algorithm proposed by gastroenterologists and patient blood management expertsca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.identifier.doihttps://doi.org/10.3389/fmed.2022.903739


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cc-by (c) Miguel Montoro et. al., 2022.
Except where otherwise noted, this item's license is described as cc-by (c) Miguel Montoro et. al., 2022.