The prediction of sediment levels in combined sewer system (CSS) would result in enormous savings in resources for their maintenance as a reduced number of inspections would be needed. In this paper, we benchmark different machine learning (ML) methodologies to improve the maintenance schedules of the sewerage and reduce the number of cleanings using historical sediment level and inspection data of the combined sewer system in the city of Barcelona. Two ML methodologies involve the use of spatial features for sediment prediction at critical sections of the sewer, where the cost of maintenance is high because of the dangerous access; one uses a regression model to predict the sediment level of a section, and the other one a binary classification model to identify whether or not a section needs cleaning. The last ML methodology is a short-term forecast of the possible sediment level in future days to improve the ability of operators to react and solve an imminent sediment level increase. Our study concludes with three different models. The spatial and short-term regression methodologies accomplished the best results with Artificial Neural Networks (ANN) with 0.76 and 0.61 R2 scores, respectively. The classification methodology resulted in a Gradient Boosting (GB) model with an accuracy score of 0.88 and an area under the curve (AUC) of 0.909.