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dc.contributor.authorPrieto Ramos, Jorge
dc.contributor.authorCorda, Andrea
dc.contributor.authorSwift, Simon
dc.contributor.authorSaderi, Laura
dc.contributor.authorde la Fuente Oliver, Gabriel
dc.contributor.authorCorcoran, Brendan
dc.contributor.authorSummers, Kim M.
dc.contributor.authorFrench, Anne T.
dc.date.accessioned2021-04-06T10:36:28Z
dc.date.available2021-04-06T10:36:28Z
dc.date.issued2021-03-28
dc.identifier.issn2076-2615
dc.identifier.urihttp://hdl.handle.net/10459.1/70921
dc.description.abstractMyxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. It varies from dogs without clinical signs to those developing left-sided congestive heart failure, leading to death. Cavalier King Charles Spaniels (CKCSs) are particularly susceptible to MMVD. We hypothesised that within the elderly CKCS population, there is a sub-cohort of MMVD-affected dogs that do not have cardiac remodelling. The objectives of the present study were (i) to determine the prevalence and the degree of cardiac remodelling associated with MMVD; and (ii) assess the effect of age, gender, and body weight on echocardiographic status in a population of aged CKCSs. A total of 126 CKCSs ≥ 8 years old were prospectively included. They all had a physical and echocardiographic examination. A systolic murmur was detected in 89% of dogs; the presence of clinical signs was reported in 19% of them; and echocardiographic evidence of MMVD was described in 100%. Despite the high prevalence, 44.4% of the dogs were clear of echocardiographic signs of cardiac remodelling. Age was significantly associated with the presence and severity of cardiac remodelling and mitral valve prolapse. Our results showed that a proportion of elderly CKCS with confirmed MMVD did not undergo advanced stages of this pathology.ca_ES
dc.description.sponsorshipThis research was funded by the British CKCS Breed Club and The Roslin Institute, University of Edinburgh.ca_ES
dc.language.isoengca_ES
dc.publisherMDPIca_ES
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/ani11040949ca_ES
dc.relation.ispartofAnimals, 2021, vol. 11, núm. 4, p. 949ca_ES
dc.rightscc-by (c) Prieto Ramos et al., 2021ca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectMyxomatous mitral valve diseaseca_ES
dc.subjectEchocardiographyca_ES
dc.subjectMitral valve degenerationca_ES
dc.subjectMitral valve prolapseca_ES
dc.subjectCardiac remodellingca_ES
dc.subjectDogca_ES
dc.subjectCardiologyca_ES
dc.subjectCavalier King Charles Spanielca_ES
dc.titleClinical and Echocardiographic Findings in an Aged Population of Cavalier King Charles Spanielsca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.identifier.idgrec031160
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.identifier.doihttps://doi.org/10.3390/ani11040949


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cc-by (c) Prieto Ramos et al., 2021
Except where otherwise noted, this item's license is described as cc-by (c) Prieto Ramos et al., 2021