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dc.contributorNEFRONA investigators
dc.contributor.authorBorràs, Mercè
dc.contributor.authorCambray Carner, Serafí
dc.contributor.authorCrespo Masip, Maria
dc.contributor.authorPérez Fontán, Miguel
dc.contributor.authorBozić Stanojević, Milica
dc.contributor.authorBermúdez López, Marcelino
dc.contributor.authorFernández i Giráldez, Elvira
dc.contributor.authorBetriu i Bars, M. Àngels
dc.contributor.authorValdivielso Revilla, José Manuel
dc.descriptionCarotid intima media thickness (cIMT) displays prognostic value as a marker of cardiovascular risk in dialysis patients. However, few data are available regarding the impact of dialysis modality on cIMT. The aim of this study is to determine whether the modality of dialysis influences cIMT values. We compared 237 peritoneal dialysis (PD) and 451 hemodialysis (HD) patients without previous cardiovascular disease included in NEFRONA, a prospective, observational and multicenter study. This cross sectional study included the determination of cIMT in 6 carotid territories by arterial ultrasound. cIMT was determined in territories without atheroma plaque and averaged. A second analysis was performed using all territories, giving a truncated cIMT value of 1,5 mm to territories presenting with atheroma plaque. Age and plaque presence at baseline were the clinical variables more closely associated to cIMT in dialysis patients. The evaluation of the impact of the modality of dialysis on cIMT showed that PD patients had lower cIMT than HD patients, both in territories with no plaques and when using truncated cIMT values. No differences were found between right and left sides, neither in cIMT or truncated cIMT values. Lineal multivariate analysis adjusted by several clinical variables showed a statistically significant association of PD with a lower cIMT (slope −0.036; SD 0.010). These results were also confirmed when truncated cIMT values were used. We conclude that the modality of dialysis has an impact on cITM. HD patients have greater global cIMT than PD patients, and PD is and independent factor associated with a lower cIMT.ca_ES
dc.description.sponsorshipThis study was funded by the intramural program of the IRBLleida, the Instituto de Salud Carlos III (RETIC RD16/0009/0011, PI15/00960, and PI16/01354), and FEDER funds ‘A way to make Europe.’ca_ES
dc.publisherFrontiers Mediaca_ES
dc.relation.isformatofReproducció del document publicat a
dc.relation.ispartofFrontiers in Physiology, 2018, vol. 9, núm. 1743ca_ES
dc.rightscc-by (c) Borràs et al., 2018ca_ES
dc.subjectIntima and media thicknessca_ES
dc.subjectCohorts studyca_ES
dc.titlePeritoneal Dialysis Is an Independent Factor Associated to Lower Intima Media Thickness in Dialysis Patients Free From Previous Cardiovascular Diseaseca_ES

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