Comparative transcriptome profile between Iberian pig varieties provides new insights into their distinct fat deposition and fatty acids content
Noguera Jiménez, José Luis
Muñoz Vázquez, Lourdes
MetadataShow full item record
The high deposition of intramuscular fat and the content of oleic fatty acid are characteristic of the Iberian pig. These two parameters present great variability and are differentiated amongst the varieties that make up the Iberian pig population. Although previous studies generated evidence for causal genes and polymorphisms associated to the adipogenic potential of the Iberian pig, there is little information about how genetic expression influences this trait's variability. The aim of this study was to analyses the expression profile between two varieties of Iberian pig (Torbiscal and Retinto) and their reciprocal crosses differentiated in their intramuscular fat (IMF) content and fatty acid (FA) composition in the Longissimus thoracis muscle using an RNA-seq approach. Our results corroborate that the Retinto variety is the fattiest amongst all studied varieties as its upregulated genes, such as FABP3 and FABP5, SLC27A1 and VEGFA among others, contribute to increasing adiposity. In its turn, Torbiscal pigs showed an upregulation of genes associated with the inhibition of fat deposition such as ADIPOQ and CPT1A. Further genetic variation analysis in these Iberian varieties showed relevant associations for SNP located within the differentially expressed genes with IMF and FA content. Thus, the differences found in the genetic architecture and the muscle transcriptome of these Iberian varieties might explain the variability in their fat content and composition and hence, their meat quality.
Is part ofAnimals, 2021, vol. 11, num. 3, p. 627
European research projects
Except where otherwise noted, this item's license is described as cc-by (c) Villaplana-Velasco et al., 2021
Showing items related by title, author, creator and subject.
Pena i Subirà, Ramona Natacha; Noguera Jiménez, José Luis; García-Santana, M. J.; González, E.; Tejeda, J. F.; Ros Freixedes, Roger; Ibáñez-Escriche, N. (Nature Research, 2019)The adipogenic nature of the Iberian pig defines many quality attributes of its fresh meat and dry-cured products. The distinct varieties of Iberian pig exhibit great variability in the genetic parameters for fat deposition ...
Genome-Wide Association Study Singles Out SCD and LEPR as the Two Main Loci Influencing Intramuscular Fat Content and Fatty Acid Composition in Duroc Pigs Ros Freixedes, Roger; Gol, Sofia; Pena i Subirà, Ramona Natacha; Tor i Naudí, Marc; Ibañez Escriche, Noelia; Dekkers, Jack C. M.; Estany Illa, Joan (Public Library of Science, 2016)Intramuscular fat (IMF) content and fatty acid composition affect the organoleptic quality and nutritional value of pork. A genome-wide association study was performed on 138 Duroc pigs genotyped with a 60k SNP chip to ...
Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles González-Prendes, Rayner; Quintanilla Aguado, Raquel; Mármol-Sánchez, Emilio; Pena i Subirà, Ramona Natacha; Ballester, Maria; Figueiredo Cardoso, Tainã; Manunza, Arianna; Casellas, Joaquim; Cánovas, Angela; Díaz, Isabel; Noguera Jiménez, José Luis; Castelló, Anna; Mercadé Carceller, Anna; Amills i Eras, Marcel (BMC (part of Springer Nature), 2019-03-04)Background: Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns of gene expression ...