The lipidome fingerprint of longevity

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2020-09-01Author
Mota Martorell, Natalia
Pradas Barriga, Irene
Galo-Licona, José Daniel
Martín-Gari, Meritxell
Sol, Joaquim
Suggested citation
Jové Font, Mariona;
Mota Martorell, Natalia;
Pradas Barriga, Irene;
Galo-Licona, José Daniel;
Martín-Gari, Meritxell;
Obis Monné, Èlia;
...
Pamplona Gras, Reinald.
(2020)
.
The lipidome fingerprint of longevity.
Molecules, 2020, vol. 25, núm. 18, p. 4343.
https://doi.org/10.3390/molecules25184343.
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Lipids were determinants in the appearance and evolution of life. Recent studies disclose the existence of a link between lipids and animal longevity. Findings from both comparative studies
and genetics and nutritional interventions in invertebrates, vertebrates, and exceptionally long-lived animal species—humans included—demonstrate that both the cell membrane fatty acid profile and lipidome are a species-specific optimized evolutionary adaptation and traits associated with longevity. All these emerging observations point to lipids as a key target to study the molecular mechanisms underlying differences in longevity and suggest the existence of a lipidome profile of long life.
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Molecules, 2020, vol. 25, núm. 18, p. 4343European research projects
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