Impact of dietary supplementation with olive and thyme phenols on alpha-tocopherol concentration in the muscle and liver of adult Wistar rats
Benavent Vallès, Alfred
MetadataShow full item record
A preliminary study to evaluate the effect of dietary supplementation with olive phenols (oleuropein, hydroxytyrosol and secoiridoids), thyme phenols and a combination of these (5 mg per kg rat weight per day) on the α-tocopherol concentrations in the muscle and liver of healthy adult Wistar rats over 21 days was conducted. In addition, the excretion of α-tocopherol through the faeces was examined. The results demonstrated that the diet supplemented with some phenolic compounds of olive and thyme increased α-tocopherol (P < 0.05) in the liver of female rats, although the α-tocopherol content in the diet of all groups was identical. In addition, a synergic effect between the olive phenols and thyme was observed. Therefore, our study indicates a protective effect of olive and thyme phenols supplemented in the diet on α-tocopherol, resulting in a higher concentration of endogenous α-tocopherol in the rat liver.
Is part ofFood and Function, 2018, vol. 9, núm. 3, p. 1433-1443
European research projects
Except where otherwise noted, this item's license is described as cc-by (c) The Royal Society of Chemistry, 2018
Showing items related by title, author, creator and subject.
Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells Catalán Santos, Úrsula; López de las Hazas Mingo, María del Carmen; Rubió Piqué, Laura; Fernández Castillejo, Sara; Pedret, Anna; De la Torre, Rafael; Motilva Casado, Mª José; Solà, Rosa (Wiley, 2015)Scope Hydroxytyrosol (HT) is the major phenolic compound in virgin olive oil (VOO) in free and conjugated forms that may exert health benefits against atherosclerosis. The native form of HT is undetectable in plasma due ...
Dose effect on the uptake and accumulation of hydroxytyrosol and its metabolites in target tissues in rats López de las Hazas Mingo, María del Carmen; Rubió Piqué, Laura; Kotronoulas, Aristotelis; De la Torre, Rafael; Solà, Rosa; Motilva Casado, Mª José (Wiley, 2015)Hydroxytyrosol (HT) is the most prominent phenolic compound of virgin olive oil and due to its scientifically validated biological activities it is entering to the market as a potentially useful supplement for cardiovascular ...
Hydroxytyrosol and its complex forms (secoiridoids) modulate aorta and heart proteome in healthy rats: Potential cardio-protective effects Catalán Santos, Úrsula; Rubió Piqué, Laura; López de las Hazas Mingo, María del Carmen; Herrero, Pol; Nadal, Pedro; Canela, Núria; Pedret, Anna; Motilva Casado, Mª José (Wiley online library, 2016)Scope Hydroxytyrosol (HT) is the major phenolic compound in virgin olive oil (VOO) in both free and complex forms (secoiridoids; SEC). Proteomics of cardiovascular tissues such as aorta or heart represents a promising tool ...