Are Obesity Indices Useful for Detecting Subclinical Atheromatosis in a Middle-Aged Population?

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2020
Author
Sánchez Peña, Enric
Sánchez, Marta
Betriu i Bars, M. Àngels
Rius, Ferran
Torres, Gerard
Purroy Garcia, Francisco
Pamplona Gras, Reinald
Ortega, Marta
López Cano, Carolina
Hernández García, Marta
Bueno Díez, Marta
Fernández i Giráldez, Elvira
Salvador, Javier
Lecube Torelló, Albert
ILERVAS project collaborators
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Sánchez Peña, Enric; Sánchez, Marta; Betriu i Bars, M. Àngels; Rius, Ferran; Torres, Gerard; Purroy Garcia, Francisco; ... ILERVAS project collaborators. (2020) . Are Obesity Indices Useful for Detecting Subclinical Atheromatosis in a Middle-Aged Population?. Obesity Facts, 2020, vol. 13, núm. 1, p. 29-39. https://doi.org/10.1159/000502696.
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Abstract
Objective: There is a close relationship between excess adiposity and cardiovascular disease. Although body mass index (BMI) is the most used approach to estimate excess weight, other anthropometric indices have been developed to measure total body and abdominal adiposity. Here, our objective was to assess the usefulness of these anthropometric indices to detect subclinical atheromatous disease. Methods: A cross-sectional study with 6,809 middle-aged subjects (mean age, 57 [53-63] years) with low to moderate cardiovascular risk from the ILERVAS project. Measures of total body fat (BMI, Clínica Universidad de Navarra - Body Adiposity Estimator [CUN-BAE], and Deurenberg's formula) and central adiposity (waist and neck circumferences, conicity index, waist-to-height ratio, Bonora's equation, the A body adiposity index, and body roundness index) were performed in all participants. Bilateral carotid and femoral ultrasound vascular studies allowed the identification of subjects with plaque. -Results: All measured indices were significantly higher in males with subclinical carotid or femoral plaques (p ≤ 0.021 for all). Also, a positive and significant correlation between all indices and the number of affected territories was found (p ≤ 0.013 for all). From the ROC analysis, all measurements identified patients with asymptomatic atheromatosis but none of them helped make clinical decisions. Regarding females, the results were less conclusive. Conclusion: Obesity indices are related to subclinical atheromatosis, especially in men, in a large cohort of middle-aged subjects. However, the indices could not detect the presence of arterial plaque, so, when used in isolation, are unlikely to be decisive.
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http://hdl.handle.net/10459.1/69508
DOI
https://doi.org/10.1159/000502696
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Obesity Facts, 2020, vol. 13, núm. 1, p. 29-39
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cc-by-nc-nd, (c) Sánchez, Enric et al., 2020
Except where otherwise noted, this item's license is described as cc-by-nc-nd, (c) Sánchez, Enric et al., 2020