Show simple item record

dc.contributor.authorMeca-Lallana, José E.
dc.contributor.authorMaurino, Jorge
dc.contributor.authorHernández Pérez, Miguel A.
dc.contributor.authorSempere, Ángel P.
dc.contributor.authorBrieva Ruiz, Luis
dc.contributor.authorGarcía-Arcelay, Elena
dc.contributor.authorTerzaghi, María
dc.contributor.authorSaposnik, Gustavo
dc.contributor.authorBallesteros, Javier
dc.description.abstractCrucial elements for achieving optimal long-term outcomes in multiple sclerosis (MS) are patient confidence and effective physician-patient communication. Patient-reported instruments may provide the means to fill the gap in currently available clinician-rated measures. The SymptoMScreen (SMSS) is a brief self-assessment tool for measuring symptom severity in 12 neurologic domains commonly affected by MS. We conducted a non-interventional study to assess the dimensional structure and item characteristics of the SMSS. A total of 218 patients with relapsing-remitting MS and mild disability (median Expanded Disability Status Scale score 2.0) were studied. Symptom severity was low (SMSS score 13.5, interquartile range 4.2-27), fatigue being the domain with the highest impact. A non-parametric item response theory, i.e., Mokken analysis, found that the SMSS is a robust one-dimensional scale (overall scalability index H 0.60) with high reliability (Cronbach's alpha 0.94). The confirmatory factor analysis model confirmed the unidimensional structure (comparative fit index 1.0, root-mean-square error of approximation 0.001). Samejima's model fitted well an unconstrained model with different item difficulties. The SMSS shows appropriate psychometric characteristics and may constitute a valuable and easy-to-implement addition to measure the symptom severity in clinical practice.ca_ES
dc.description.sponsorshipThis study was funded by the Medical Department of Roche Farma Spain. The sponsor also funded the journals Rapid Service feeca_ES
dc.relation.isformatofReproducció del document publicat a
dc.relation.ispartofNeurology and Therapy, 2020, vol. 9, núm. 1, p. 173-179ca_ES
dc.rightscc-by-nc (c) Meca-Lallana, 2020ca_ES
dc.subjectMultiple sclerosisca_ES
dc.subjectPatient-reported outcomeca_ES
dc.subjectPsychometric methodsca_ES
dc.subjectSymptom severityca_ES
dc.titlePsychometric Properties of the SymptoMScreen Questionnaire in a Mild Disability Population of Patients with Relapsing–Remitting Multiple Sclerosis: Quantifying the Patient’s Perspectiveca_ES

Files in this item


This item appears in the following Collection(s)

Show simple item record

cc-by-nc (c) Meca-Lallana, 2020
Except where otherwise noted, this item's license is described as cc-by-nc (c) Meca-Lallana, 2020