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dc.contributor.authorGasa Falcón, Ariadna
dc.contributor.authorOdriozola Serrano, Isabel
dc.contributor.authorOms Oliu, Gemma
dc.contributor.authorMartín Belloso, Olga
dc.date.accessioned2020-03-30T07:27:08Z
dc.date.available2020-03-30T07:27:08Z
dc.date.issued2020-03-11
dc.identifier.issn2304-8158
dc.identifier.urihttp://hdl.handle.net/10459.1/68365
dc.description.abstractAcquisition of a healthy lifestyle through diet has driven the food manufacturing industry to produce new food products with high nutritional quality. In this sense, consumption of bioactive compounds has been associated with a decreased risk of suffering chronic diseases. Nonetheless, due to their low solubility in aqueous matrices, high instability in food products during processing and preparation as well as poor bioavailability, the use of such compounds is sometimes limited. Recent advancements in encapsulation and protection of bioactive compounds has opened new possibilities for the development of novel food products. In this direction, the present review is attempting to describe encapsulation achievements, with special attention to nanostructured lipid-based delivery systems, i.e., nanoemulsions, multi-layer emulsions and liposomes. Functionality of bioactive compounds is directly associated with their bioavailability, which in turn is governed by several complex processes, including the passage through the gastrointestinal tract and transport to epithelial cells. Therefore, an overview of recent research on the properties of these nanostructured lipid-based delivery systems with a strong impact on the functionality of bioactive compounds will be also provided. Nanostructured lipid-based delivery systems might be used as a potential option to enhance the solubility, stability, absorption and, ultimately, functionality of bioactive compounds. Several studies have been performed in this line, modifying the composition of the nanostructures, such as the lipid-type or surfactants. Overall, influencing factors and strategies to improve the efficacy of encapsulated bioactive compounds within nanostructures have been successfully identified. This knowledge can be used to design effective targeted nanostructured lipid-based delivery systems for bioactive compounds. However, there is still a lack of information on food interactions, toxicity and long-term consumption of such nanostructures.ca_ES
dc.description.sponsorshipThis work was funded by the project AGL2015-65975-R (FEDER, MINECO, UE) and project RTI2018-094268-B-C21 (MCIU, AEI; FEDER, UE).ca_ES
dc.language.isoengca_ES
dc.publisherMDPIca_ES
dc.relationMINECO/PN2013-2016/AGL2015-65975-Rca_ES
dc.relationMINECO/PN2017-2020/RTI2018-094268-B-C21ca_ES
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/foods9030325ca_ES
dc.relation.ispartofFoods, 2020, vol. 9, núm. 3, article number 325, p. 1-21ca_ES
dc.rightscc-by (c) Gasa Falcón, Ariadna et al., 2020ca_ES
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectLipid digestibilityca_ES
dc.subjectBioaccessibilityca_ES
dc.subjectNanoemulsionca_ES
dc.subjectLiposomesca_ES
dc.subjectBioactive compoundsca_ES
dc.titleNanostructured lipid-based delivery systems as a strategy to increase functionality of bioactive compoundsca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.identifier.doihttps://doi.org/10.3390/foods9030325


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cc-by (c) Gasa Falcón, Ariadna et al., 2020
Except where otherwise noted, this item's license is described as cc-by (c) Gasa Falcón, Ariadna et al., 2020