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dc.contributor.authorSandoval-Ramírez, Berner Andrée
dc.contributor.authorCatalán Santos, Úrsula
dc.contributor.authorFernandez-Castillejo, Sara
dc.contributor.authorRubió Piqué, Laura
dc.contributor.authorMacià i Puig, Ma Alba
dc.contributor.authorSolà, Rosa
dc.date.accessioned2019-06-19T14:34:38Z
dc.date.available2019-06-19T14:34:38Z
dc.date.issued2018-10-22
dc.identifier.issn1520-5118
dc.identifier.urihttp://hdl.handle.net/10459.1/66470
dc.description.abstractAnthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13 publications met inclusion criteria. Extracted information included animal model employed, administration route, doses, analysis method, and ACN concentration values in tissues. Total ACN concentrations were detected in mice kidney (2.17 × 105 pmol/g), liver (1.73 × 105 pmol/g), heart (3.6 × 103 pmol/g), and lung (1.16 × 105 pmol/g); and in pig brain (6.08 × 103 pmol/g). ACNs showed a predominance of parent ACNs in long-term experiments versus an ACN metabolite predominance in short-term experiments. ACNs detected in animal tissues, such as cyanidin-3-glucoside, suggest it may have an important role in human health. This information could be useful to determine proper ACN-intake biomarkers in biological samples in futures studies.ca_ES
dc.description.sponsorshipThe AppleCOR Project (Subproject AGL2016-76943-C2-2-R and Suproject AGL2016-76943-C2-1-R) has been possible with the support of Ministerio de Economia , Indústria y Competitividad, the Agencia Estatal de Investigación (AEI) and the European Regional Development Fund (ERDF). B.A.S.-R. enjoys a 2017MFP-COFUND-30 predoctoral fellowship contract. This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 713679 and from the Universitat Rovira i Virgili (URV). Ú.C. has a Pla estratègic de recerca i innovació en salut (PERIS) postdoctoral grant (SLT002/16/00239; Catalunya, Spain) from Generalitat de Catalunya; NFOC-Salut group is a consolidated research group of Generalitat de Catalunya, Spain (2017 SGR 522).ca_ES
dc.language.isoengca_ES
dc.publisherAmerican Chemical Societyca_ES
dc.relationMINECO/PN2013-2016/AGL2016-76943-C2-1-Rca_ES
dc.relationMINECO/PN2013-2016/AGL2016-76943-C2-2-Rca_ES
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1021/acs.jafc.8b04014ca_ES
dc.relation.ispartofJournal of Agricultural and Food Chemistry, 2018, vol. 66, núm. 44, p. 11531-11543ca_ES
dc.rights(c) American Chemical Society, 2018. This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.ca_ES
dc.subjectCompostos fenòlicsca_ES
dc.subjectTissue bioavailabilityca_ES
dc.subjectAnimal studiesca_ES
dc.subject.otherAntocianinesca_ES
dc.titleAnthocyanin tissue bioavailability in animals: possible implications for human health. A systematic reviewca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.identifier.idgrec029955
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.identifier.doihttps://doi.org/10.1021/acs.jafc.8b04014
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/713679/EU/MFPca_ES


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