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dc.contributor.authorPena i Subirà, Ramona Natacha
dc.contributor.authorNoguera Jiménez, José Luis
dc.contributor.authorGarcía-Santana, M. J.
dc.contributor.authorGonzález, E.
dc.contributor.authorTejeda, J. F.
dc.contributor.authorRos Freixedes, Roger
dc.contributor.authorIbáñez-Escriche, N.
dc.date.accessioned2019-03-18T11:33:31Z
dc.date.available2019-03-18T11:33:31Z
dc.date.issued2019
dc.identifier.issn2045-2322
dc.identifier.urihttp://hdl.handle.net/10459.1/65962
dc.description.abstractThe adipogenic nature of the Iberian pig defines many quality attributes of its fresh meat and dry-cured products. The distinct varieties of Iberian pig exhibit great variability in the genetic parameters for fat deposition and composition in muscle. The aim of this work is to identify common and distinct genomic regions related to fatty acid composition in Retinto, Torbiscal, and Entrepelado Iberian varieties and their reciprocal crosses through a diallelic experiment. In this study, we performed GWAS using a high density SNP array on 382 pigs with the multimarker regression Bayes B method implemented in GenSel. A number of genomic regions showed strong associations with the percentage of saturated and unsaturated fatty acid in intramuscular fat. In particular, five regions with Bayes Factor >100 (SSC2 and SSC7) or >50 (SSC2 and SSC12) explained an important fraction of the genetic variance for miristic, palmitoleic, monounsaturated (>14%), oleic (>10%) and polyunsaturated (>5%) fatty acids. Six genes (RXRB, PSMB8, CHGA, ACACA, PLIN4, PLIN5) located in these regions have been investigated in relation to intramuscular composition variability in Iberian pigs, with two SNPs at the RXRB gene giving the most consistent results on oleic and monounsaturated fatty acid content.ca_ES
dc.description.sponsorshipThe authors would like to acknowledge the help of Inga Food S.A. and their support staff in setting up the experiment (E. Magallón, M. Ramos, L. Muñoz, and P. Diaz) and Dr L. Varona from University of Zaragoza for discussion. This study was funded by the INIA grant RTA 2012-0054-C02-01 and the Centre for the Development of Industrial Technology agreement IDI-20140447.ca_ES
dc.language.isoengca_ES
dc.publisherNature Researchca_ES
dc.relation.isformatofReproducció del document publicat a:https://doi.org/10.1038/s41598-019-38622-7ca_ES
dc.relation.ispartofScientific Reports, 2015, vol. 9, núm. 2031, p. 1-9ca_ES
dc.rightscc-by, (c) Pena et al., 2019ca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.otherPorcs ibèrics
dc.subject.otherCarn de porc
dc.titleFive genomic regions have a major impact on fat composition in Iberian pigsca_ES
dc.typeinfo:eu-repo/semantics/articleca_ES
dc.identifier.idgrec028457
dc.type.versioninfo:eu-repo/semantics/publishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.identifier.doihttps://doi.org/10.1038/s41598-019-38622-7


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cc-by, (c) Pena et al., 2019
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