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dc.contributor.authorAdam, Nathalie
dc.contributor.authorSchmitt, Claudia
dc.contributor.authorGalceran i Nogués, Josep
dc.contributor.authorCompanys Ferran, Encarnació
dc.contributor.authorVakourov, Alex
dc.contributor.authorWallace, Rachel
dc.contributor.authorKnapen, Dries
dc.contributor.authorBlust, Ronny
dc.date.accessioned2018-11-20T12:55:00Z
dc.date.available2018-11-20T12:55:00Z
dc.date.issued2014-11
dc.identifier.issn1743-5390
dc.identifier.urihttp://hdl.handle.net/10459.1/65152
dc.description.abstractIn this study, the effect of ZnO nanoparticles and ZnCl2 on growth, reproduction and accumulation of Daphnia magna was determined in a 21 day chronic toxicity test. Different techniques were used to distinguish between the Zn2+, dissolved, nanoparticle and aggregated fraction in the daphnia test medium. The results showed similar chronic effects on growth, reproduction and accumulation for the ZnO nanoparticles (EC10, 20, 50 reproduction: 0.029, 0.048, 0.113 mg Zn/l) and the ZnCl2 (EC10, 20, 50 reproduction: 0.014, 0.027, 0.082 mg Zn/l). A large fraction of the nanoparticles rapidly dissolved after introduction in the exposure medium. However, also aggregation of nanoparticles was observed but after 48 hours of exposure most of these ZnO aggregates were dissolved. Based on the combined dissolution kinetics and toxicity results it can be concluded that the toxicological effects of ZnO nanoparticles at the chronic level can be largely attributed to the dissolved fraction rather than the initially formed aggregates.
dc.description.sponsorshipThis study, making part of the ENNSATOX-project, was funded by the EU (NMP4-SL-2009-229244). The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. Financial support from the Spanish Ministry of Education and Science (Project CTQ2009-07831) and from the “Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement de la Generalitat de Catalunya” (2009SGR00465) is acknowledged as well.
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherTaylor & Francis
dc.relationMCINN/PN2008-2011/CTQ2009-07831
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.3109/17435390.2013.822594
dc.relation.ispartofNanotoxicology, 2014, vol. 8, num. 7, p. 709-717
dc.rights(c) Informa Uk, Ltd., 2014
dc.subjectNanotoxicity
dc.subjectZinc
dc.subjectReproduction
dc.subjectDaphnia
dc.titleThe chronic toxicity of ZnO nanoparticles and ZnCl2 to Daphnia magna and the use of different methods to assess nanoparticle aggregation and dissolution.
dc.typeinfo:eu-repo/semantics/article
dc.date.updated2018-11-20T12:55:00Z
dc.identifier.idgrec020075
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.identifier.doihttps://doi.org/10.3109/17435390.2013.822594


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