Universitat de Lleida
    • English
    • català
    • español
  • English 
    • English
    • català
    • español
  • Login
Repositori Obert UdL
View Item 
  •   Home
  • Recerca
  • Tecnologia dels Aliments
  • Articles publicats (Tecnologia dels Aliments)
  • View Item
  •   Home
  • Recerca
  • Tecnologia dels Aliments
  • Articles publicats (Tecnologia dels Aliments)
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models

Thumbnail
View/Open
014717.pdf (402.4Kb)
Issue date
2010
Author
Serra Maqueda, Aida
Macià i Puig, Ma Alba
Romero Fabregat, Mª Paz
Valls, Josep
Bladé, Cinta
Arola i Ferrer, Lluís
Motilva Casado, Mª José
Suggested citation
Serra Maqueda, Aida; Macià i Puig, Ma Alba; Romero Fabregat, Mª Paz; Valls, Josep; Bladé, Cinta; Arola i Ferrer, Lluís; Motilva Casado, Mª José; . (2010) . Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models. British Journal of Nutrition, 2010, vol. 103, p. 944-952. https://doi.org/10.1017/S0007114509992741.
Impact


Web of Science logo    citations in Web of Science

Scopus logo    citations in Scopus

Google Scholar logo  Google Scholar
Share
Export to Mendeley
Metadata
Show full item record
Abstract
Among procyanidins (PC), monomers, such as catechin and epicatechin, have been widely studied, whereas dimer and trimer oligomers have received much less attention, despite their abundance in our diet. Recent studies have showed that as dimers and trimers could be important in determining the biological effects of procyanidin-rich food, understanding their bioavailability and metabolism is fundamental. The purpose of the present work is to study the stability of PC under digestion conditions, the metabolism and the bioavailability by using a combination of in vitro and in vivo models. Simultaneously, the matrix effect of a carbohydrate-rich food on the digestibility and bioavailability of PC is investigated. The results show a high level of stability of PC under gastric and duodenal digestion conditions. However, the pharmacokinetic study revealed limited absorption. Free forms of dimers and trimers have been detected in rat plasma, reaching the maximum concentration 1 h after oral intake of a grape seed extract.
URI
http://hdl.handle.net/10459.1/64880
DOI
https://doi.org/10.1017/S0007114509992741
Is part of
British Journal of Nutrition, 2010, vol. 103, p. 944-952
European research projects
Collections
  • Publicacions de projectes de recerca del Plan Nacional [2217]
  • Articles publicats (Tecnologia dels Aliments) [495]

Related items

Showing items related by title, author, creator and subject.

  • Effect of the co-occurring components from olive oil and thyme extracts on the antioxidant status and its bioavailability in an acute ingestion in rats 

    Rubió Piqué, Laura; Serra Maqueda, Aida; Chen, O.; Macià i Puig, Ma Alba; Romero Fabregat, Mª Paz; Covas Planells, María Isabel; Solà, Rosa; Motilva Casado, Mª José (Royal Society of Chemistry (Gran Bretanya), 2014-01-02)
    The aim of this work was to examine whether bioactives in thyme could enhance the antioxidant capacity of phenolics in virgin olive oil and their bioavailability in Wistar rats. After acute oral administration of extracts ...
  • Flavanol metabolites distribute in visceral adipose depots after a long-term intake of grape seed proanthocyanidin extract in rats 

    Serra Maqueda, Aida; Bladé, Cinta; Arola i Ferrer, Lluís; Macià i Puig, Ma Alba; Motilva Casado, Mª José (Cambridge University Press, 2013)
    A considerable number of epidemiological investigations and intervention studies have supported an association between the intake of flavanol- and proanthocyanidin-containing foods and a decreased risk of metabolic diseases. ...
  • Application of in vitro gastrointestinal digestion and colonic fermentation models to pomegranate products (juice, pulp and peel extract) to study the stability and catabolism of phenolic compounds 

    Mosele, Juana; Macià i Puig, Ma Alba; Romero Fabregat, Mª Paz; Motilva Casado, Mª José; Rubió Piqué, Laura (John Wiley & Sons, 2015)
    Pomegranate fruit contains a wide range of phenolic compounds that have been related to several health benefits. The stability of pomegranate phenols during digestion was tested by the application of in vitro gastrointestinal ...

Contact Us | Send Feedback | Legal Notice
© 2021 BiD. Universitat de Lleida
Metadata subjected to 
 

 

Browse

All of the repositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

Statistics

View Usage Statistics

D'interès

Política institucional d'accés obertDiposita les teves publicacionsDiposita dades de recercaSuport a la recerca

Contact Us | Send Feedback | Legal Notice
© 2021 BiD. Universitat de Lleida
Metadata subjected to