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dc.contributor.authorGranado Casas, Minerva
dc.contributor.authorRamírez-Morros, Anna
dc.contributor.authorMartín, Mariona
dc.contributor.authorReal, Jordi
dc.contributor.authorAlonso, Núria
dc.contributor.authorValldeperas, Xavier
dc.contributor.authorTraveset Maeso, Alicia
dc.contributor.authorRubinat, Esther
dc.contributor.authorAlcubierre Calvo, Núria
dc.contributor.authorHernández García, Marta
dc.contributor.authorPuig-Domingo, Manuel
dc.contributor.authorLecube Torelló, Albert
dc.contributor.authorCastelblanco Echavarría, Esmeralda
dc.contributor.authorMauricio Puente, Dídac
dc.description.abstractMedical nutrition therapy is an important part of the management of type 1 diabetes mellitus (T1DM). Proper adherence to a healthy diet may have a favorable impact on diabetes management and its diabetic complications. Our aim was to assess differences in food and nutrient intake of type 1 diabetic patients with and without diabetic retinopathy (DR). This was a two-center, cross-sectional study in patients with T1DM, with and without DR. Subjects were recruited from the outpatient clinic of the two participating centers. A validated food frequency questionnaire was administered. A total of 103 T1DM patients with DR and 140 T1DM patient without DR were recruited. Subjects with DR showed a lower intake of total fat (p = 0.036) than that of their non-DR counterparts. DR was associated with increasing age (p = 0.004), hypertension (p < 0.001), and diabetes duration (p < 0.001), however there was a negative association with high educational level (p = 0.018). The multivariate-adjusted analysis showed that the intake of complex carbohydrates was positively related to the presence of DR (p = 0.031). In contrast, the intakes of total fat (p = 0.009), monounsaturated fatty acids (MUFAs) (p = 0.012), oleic acid (p = 0.012), and vitamin E (p = 0.006) were associated with the absence of DR. As conclusions, the intake of total MUFAs, oleic acid, and vitamin E is associated with a lower frequency of DR in patients with T1DM. These results suggest a potential protective effect of these lipid components for DR.
dc.description.sponsorshipThis research was funded by grants PI12/00183 and PI15/00625 from Instituto de Salud Carlos III, Ministry of Economy and Competitiveness, Spain. CIBERDEM is an initiative from Instituto de Salud Carlos III (Plan Nacional de I+D+I and Fondo Europeo de Desarrollo Regional), Spain. M.G.-C. holds a predoctoral fellowship from Ministerio de Educación, Cultura y Deporte, FPU15/03005, Spain
dc.relation.isformatofReproducció del document publicat a:
dc.relation.ispartofNutrients, 2018, vol. 10, num. 1184, p. 1-10
dc.rightscc-by (c) Granado Casas, Minerva et al., 2018
dc.subject.classificationRetinopatia diabètica
dc.subject.classificationÀcids grassos
dc.subject.classificationÀcid oleic
dc.subject.otherDiabetic retinopathy
dc.subject.otherFatty acids
dc.subject.otherOleic acid
dc.titleType 1 diabetic subjects with diabetic retinopathy show an unfavorable pattern of fat intake

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cc-by (c) Granado Casas, Minerva et al., 2018
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