Cancer and quality of life. Breast cancer overdiagnosis and design of an intervention to improve the quality of life of oncological patients in palliative care
Dusso Rosso, Adriana
Universitat de Lleida. Departament de Ciències Mèdiques Bàsiques
MetadataShow full item record
Early detection of breast cancer (BC) with mammography may cause overdiagnosis and overtreatment. In the other extreme, for advanced cancer patients in palliative care quality of life is the most important outcome. Our aims are: to model invasive BC incidence trends in Catalonia and quantify the extent of BC overdiagnosis; to perform a systematic review of all the clinical outcomes reported in cancer after the supplementation with vitamin D (VD); to assess serum VD deficiency and its relationship with quality of life, fatigue, and physical and functional performance; and to design a randomized controlled trial (VIDAFACT) to assess VD effectiveness in increasing quality of life. Our estimates support the existence of overdiagnosis in Catalonia attributable to mammography usage. The results from both the cross-sectional study and the systematic review, support the need for VIDAFACT to provide data about VD supplementation effectiveness on improving overall quality of life.
European research projects
- Tesis Doctorals 
Showing items related by title, author, creator and subject.
Feasibility and acceptability of personalised breast cancer screening (DECIDO study): protocol of a single-arm proof-of-concept trial Pons Rodríguez, Anna; Forné Izquierdo, Carles; Vilaplana Mayoral, Jordi; Cruz Esteve, María Inés; Sánchez-López, Isabel; Reñé Reñé, Mercè; Cazorla, Cristina; Hernández Andreu, Marta; Galindo Ortego, Gisela; Llorens Gabandé, Montserrat; Laza-Vásquez, Celmira; Balaguer Llaquet, Pau; Martínez Alonso, Montserrat; Rué i Monné, Montserrat (BMJ Publishing Group, 2020-12-23)Introduction Personalised cancer screening aims to improve benefits, reduce harms and being more cost-effective than age-based screening. The objective of the DECIDO study is to assess the acceptability and feasibility of ...
Assessment of the effects of decision aids about breast cancer screening: a systematic review and meta-analysis Martínez Alonso, Montserrat; Carles Lavila, Misericordia; Pérez Lacasta, María José; Pons Rodríguez, Anna; Garcia, Montse; Rué i Monné, Montserrat (BMJ Publishing Group, 2017)The aim of this systematic review and meta-analysis of randomised controlled trials (RCTs) and observational studies is to assess the effect of decision aids (DAs) in women aged 50 and below facing the decision to be ...
Pons Rodríguez, Anna; Martínez Alonso, Montserrat; Perestelo Pérez, Lilisbeth; Garcia, Montse; Sala i Serra, Maria; Rué i Monné, Montserrat (Elsevier, 2020-01-16)Objective To evaluate the effect of receiving information about the benefits and harms of breast cancer screening in informed choice, according to educational level. Method Secondary analysis of a randomized, controlled ...