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dc.contributor.authorGol, Sofia
dc.contributor.authorRos Freixedes, Roger
dc.contributor.authorZambonelli, P.
dc.contributor.authorTor i Naudí, Marc
dc.contributor.authorPena i Subirà, Ramona Natacha
dc.contributor.authorBraglia, S.
dc.contributor.authorZappaterra, M.
dc.contributor.authorEstany Illa, Joan
dc.contributor.authorDavoli, R.
dc.date.accessioned2018-05-29T08:57:59Z
dc.date.available2018-05-29T08:57:59Z
dc.date.issued2016-02
dc.identifier.issn0931-2668
dc.identifier.urihttp://hdl.handle.net/10459.1/63444
dc.description.abstractThe perilipins (PLIN) belong to a family of structural proteins that play a role regulating intracellular lipid storage and mobilization. Here, PLIN1 and PLIN2 have been evaluated as candidate genes for growth, carcass and meat quality traits in pigs. A sample of 607 Duroc pigs were genotyped for two single-nucleotide polymorphisms, one in intron 2 of the PLIN1 gene (JN860199:g.173G>A) and the other at the 3' untranslated region of the PLIN2 gene (GU461317:g.98G>A). Using a Bayesian approach, we have been able to find evidence of additive, dominant and epistatic associations of the PLIN1 and PLIN2 polymorphisms with early growth rate and carcass length. However, the major effects were produced by the dominant A allele at the PLIN2 polymorphism, which also affected the carcass lean weight. Thus, pigs carrying an additional copy of the A allele at the g.98G>A PLIN2 polymorphism had a probability of at least 98% of producing carcasses with heavier lean weight (+0.41 kg) and ham weight (+0.10 kg). The results obtained indicate that the PLIN2 polymorphism could be a useful marker for lean growth. In particular, it may help to reduce the undesired negative correlated response in lean weight to selection for increased intramuscular fat content, a common scenario in some Duroc lines involved in the production of high quality pork products.
dc.description.sponsorshipThis work was partially funded by national projects AGL2009-09779 and AGL2012-33529 (Ministry of Education and Innovation, Spain) and AGER-HEPI- GET grant N. 2011-0279 (Italy). S. Gol is recipient of a PhD scholarship from MINECO, Spain (BES-2014- FPU13/04975).
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherWiley
dc.relationMICINN/PN2008-2011/AGL2009-09779
dc.relationMICINN/PN2008-2011/AGL2012-33529
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1111/jbg.12159
dc.relation.ispartofJournal of Animal Breeding and Genetics, 2016, vol. 133, núm. 1, p. 24-30
dc.rights(c) Blackwell Verlag GmbH, 2015
dc.subjectBody weigh
dc.subjectDuroc pigs
dc.subjectFat
dc.subjectGenetic markers
dc.subject.otherGenètica animal
dc.subject.otherGenètica molecular
dc.subject.otherAnimals--Cria i desenvolupament
dc.titleRelationship between perilipin genes polymorphisms and growth, carcass and meat quality traits in pigs
dc.typeinfo:eu-repo/semantics/article
dc.date.updated2018-05-29T08:57:59Z
dc.identifier.idgrec022506
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.identifier.doihttps://doi.org/10.1111/jbg.12159


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