Diabetic retinopathy is associated with the presence and burden of subclinical carotid atherosclerosis in type 1 diabetes
Castelblanco Echavarría, Esmeralda
Traveset Maeso, Alicia
MetadataShow full item record
Background: Cardiovascular (CV) disease due to atherosclerosis is a major cause of morbidity and mortality in adult patients with diabetes, either type 1 or type 2 diabetes. The aim of the study was to assess the association of the frequency and the burden of subclinical carotid atherosclerotic disease in patients with type 1 diabetes according to the presence and severity of diabetic retinopathy (DR). Methods: A cross-sectional study was conducted in 340 patients with type 1 diabetes (41.5% with DR), and in 304 non-diabetic individuals. All participants were free from previous CV disease and chronic kidney disease (CKD). B-mode carotid ultrasound imaging was performed in all the study subjects. Patients with type 1 diabetes underwent a full eye examination, and DR patients were divided into two groups: mild disease and advanced disease. Results: In the group of patients with type 1 diabetes, the percentage of patients with carotid plaques was higher in those with DR compared with those without DR (44.7% vs. 24.1%, p < 0.001). Patients with DR also presented a higher incidence of ≥ 2 carotid plaques (25.5% vs. 11.1%, p < 0.001). Apart from other traditional cardiovascular risk factors, the presence of advanced stages of DR was independently associated with the presence (p = 0.044) and the burden (≥ 2 carotid plaques; p = 0.009) of subclinical carotid atherosclerosis. Conclusions: In patients with type 1 diabetes without previous CV disease or established CKD, the presence of advanced stages of DR is associated with a higher atherosclerotic burden in the carotid arteries. The presence of DR identifies patients at risk for carotid atherosclerotic disease.
Is part ofCardiovascular Diabetology, 2018, vol. 17, núm. 66, p. 1-10
European research projects
The following license files are associated with this item:
Except where otherwise noted, this item's license is described as cc-by (c) Carbonell, Marc et al., 2018
Showing items related by title, author, creator and subject.
Granado Casas, Minerva; Ramírez-Morros, Anna; Martín, Mariona; Real, Jordi; Alonso, Núria; Valldeperas, Xavier; Traveset Maeso, Alicia; Rubinat, Esther; Alcubierre Calvo, Núria; Hernández García, Marta; Puig-Domingo, Manuel; Lecube Torelló, Albert; Castelblanco Echavarría, Esmeralda; Mauricio Puente, Dídac (MDPI, 2018-08-29)Medical nutrition therapy is an important part of the management of type 1 diabetes mellitus (T1DM). Proper adherence to a healthy diet may have a favorable impact on diabetes management and its diabetic complications. Our ...
Ultrasound Tissue Characterization of Carotid Plaques Differs Between Patients with Type 1 Diabetes and Subjects without Diabetes Castelblanco Echavarría, Esmeralda; Betriu i Bars, M. Àngels; Hernández, Marta; Granado Casas, Minerva; Ortega, Emilio; Soldevila, Berta; Ramírez-Morros, Anna; Franch-Nadal, Josep; Puig-Domingo, Manuel; Fernández i Giráldez, Elvira; Avogaro, Angelo; Alonso, Núria; Mauricio Puente, Dídac (MDPI, 2019-03-28)The aim of the study was to investigate ultrasound tissue characterization of carotid plaques in subjects with and without diabetes type 1 (T1D). B-mode carotid ultrasound was performed to assess the presence and type of ...
Poorer Quality of Life and Treatment Satisfaction is Associated with Diabetic Retinopathy in Patients with Type 1 Diabetes without Other Advanced Late Complications Granado Casas, Minerva; Castelblanco Echavarría, Esmeralda; Ramírez-Morros, Anna; Martín, Mariona; Alcubierre Calvo, Núria; Martínez Alonso, Montserrat; Valldeperas, Xavier; Traveset Maeso, Alicia; Rubinat, Esther; Lucas-Martin, Ana; Hernández, Marta; Alonso, Núria; Mauricio Puente, Dídac (MDPI, 2019-03-18)Diabetic retinopathy (DR) may potentially cause vision loss and affect the patient's quality of life (QoL) and treatment satisfaction (TS). Using specific tools, we aimed to assess the impact of DR and clinical factors on ...