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dc.contributor.authorKoo, Chieh-Yang
dc.contributor.authorSánchez de la Torre, Alicia
dc.contributor.authorLoo, Germaine
dc.contributor.authorSánchez de la Torre, Manuel
dc.contributor.authorZhang, Junjie
dc.contributor.authorDurán-Cantolla, Joaquín
dc.contributor.authorLi, Ruogu
dc.contributor.authorMayós Pérez, Mercè
dc.contributor.authorSethi, Rithi
dc.contributor.authorAbad, Jorge
dc.contributor.authorDrager, Luciano
dc.contributor.authorColoma, Ramón
dc.contributor.authorHein, Thet
dc.contributor.authorHo, Hee-Hwa
dc.contributor.authorJim, Man-Hong
dc.contributor.authorOng, Thun-How
dc.contributor.authorTai, Bee-Choo
dc.contributor.authorAldomá, Albina
dc.contributor.authorLee, Chi-Hang
dc.contributor.authorBarbé Illa, Ferran
dc.description.abstractObjective: Obstructive sleep apnea (OSA) is an increasing yet under-recognized risk factor for acute coronary syndrome (ACS). We sought to determine the effects of ethnicity on the prevalence of OSA in patients presenting with ACS who participated in an overnight sleep study. Methods: A pooled analysis using patient-level data from the ISAACC Trial and Sleep and Stent Study was performed. Using the same portable diagnostic device and scoring criteria, OSA was defined as an apnea-hypopnea index of ≥15. Results: A total of 1961 patients were analyzed, including Spanish (53.6%, n=1050), Chinese (25.5%, n=500), Indian (12.0%, n=235), Malay (6.1%, n=119), Brazilian (1.7%, n=34) and Burmese (1.2%, n=23) populations. Significant differences in body mass index (BMI) were found among the various ethnic groups, averaging from 25.3 kg/m2 for Indians and 25.4 kg/m2 for Chinese to 28.6 kg/m2 for Spaniards. The prevalence of OSA was highest in the Spanish (63.1%), followed by the Chinese (50.2%), Malay (47.9%), Burmese (43.5%), Brazilian (41.2%), and Indian patients. The estimated odds ratio of BMI on OSA was highest in the Chinese population (1.17; 95% confidence interval: 1.10–1.24), but was not significant in the Spanish, Burmese or Brazilian populations. The area under the curve (AUC) for the Asian patients (ranging from 0.6365 to 0.6692) was higher than that for the Spanish patients (0.5161). Conclusion: There was significant ethnic variation in the prevalence of OSA in patients with ACS, and the magnitude of the effect of BMI on OSA was greater in the Chinese population than in the Spanish patients.ca_ES
dc.description.sponsorshipThe authors gratefully acknowledge the staff working at the participating centers of ISAACC and Sleep and Stent Study for their contribution to patient recruitmentca_ES
dc.publisherAustralian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS)ca_ES
dc.publisherCardiac Society of Australia and New Zealand (CSANZ)ca_ES
dc.relation.isformatofVersió postprint del document publicat a
dc.relation.ispartofHeart, Lung and Circulation, 2017, vol. 26, núm. 5, p. 486-494ca_ES
dc.rightscc-by-nc-nd (c) Elsevier, 2016ca_ES
dc.subjectAcute coronary syndromeca_ES
dc.subjectObstructive sleep apnoeaca_ES
dc.titleEffects of Ethnicity on the Prevalence of Obstructive Sleep Apnoea in Patients with Acute Coronary Syndrome: A Pooled Analysis of the ISAACC Trial and Sleep and Stent Study.ca_ES

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cc-by-nc-nd (c) Elsevier, 2016
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