The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case–control study, Spain, 2013/14 and 2014/15
Fernandez, Maria Amelia
Mayoral, José María
MetadataShow full item record
Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case–control study was conducted in 20 Spanish hospitals during
2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22–47). VE was 51% (95% CI: 15–71) in patients without high-risk medical conditions and 30% (95% CI: 14–44) in patients with them. VE was 39% (95% CI: 20–53) in patients aged 65–79 years and 34% (95% CI: 11–51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.
Is part ofEurosurveillance, 2017, vol. 22, núm. 34, p. 1-8
The following license files are associated with this item:
Showing items related by title, author, creator and subject.
Domínguez García, Àngela; Soldevila, Núria; Toledo, Diana; Godoy i García, Pere; Castilla, Jesús; Force, Lluís; Morales, María; Mayoral, José María; Egurrola, Mikel; Tamames, Sonia; Martín, Vicente; Astray, Jenaro (Public Library of Science, 2016)Vaccination of the elderly is an important factor in limiting the impact of influenza in the community. The aim of this study was to investigate the factors associated with influenza vaccination coverage in hospitalized ...
Knowledge of and attitudes to influenza vaccination in healthy primary healthcare workers in Spain, 2011-2012 Domínguez García, Àngela; Godoy i García, Pere; Castilla, Jesús; Soldevila, Núria; Toledo, Diana; Astray, Jenaro; Mayoral, José María; Tamames, Sonia; García-Gutiérrez, Susana; González-Candelas, Fernando; Martín, Vicente; Díaz, José; Torner Gràcia, Núria; CIBERESP Working Group for the Survey on Influenza Vaccination in Primary Health Care Workers (Public Library of Science (PLoS), 2013)Annual influenza vaccination is recommended for healthcare workers, but many do not follow the recommendation. The objective of this study was to investigate the factors associated with seasonal influenza vaccination in ...
Influenza vaccination of primary healthcare physicians may be associated with vaccination in their patients: a vaccination coverage study Godoy i García, Pere; Castilla, Jesús; Mayoral, José María; Martín, Vicente; Astray, Jenaro; Torner Gràcia, Núria; Toledo, Diana; Soldevila, Núria; González-Candelas, Fernando; García-Gutiérrez, Susana; Diaz-Borrego, José; Tamames, Sonia; Domínguez García, Àngela (BioMed Central, 2015)Background: To assess the contribution of physician-related factors, especially their influenza vaccine status, in the vaccination coverage of their patients. Methods: A study of vaccination coverage was carried out in ...