Browsing Articles publicats (IRBLleida) by Subject "Sistemes biològics -- Models matemàtics"
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Identifying the preferred subset of enzymatic profiles in nonlinear kinetic metabolic models via multiobjective global optimization and pareto filters
(Public Library of Science (PLoS), 2012)Optimization models in metabolic engineering and systems biology focus typically on optimizing a unique criterion, usually the synthesis rate of a metabolite of interest or the rate of growth. Connectivity and non-linear ... -
Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models
(BioMed Central, 2011)Background: Design of newly engineered microbial strains for biotechnological purposes would greatly benefit from the development of realistic mathematical models for the processes to be optimized. Such models can then be ...