Now showing items 1-10 of 10

    • Bronchial Aspirate-Based Profiling Identifies MicroRNA Signatures Associated With COVID-19 and Fatal Disease in Critically Ill Patients 

      Molinero, Marta; Benítez, Iván; González, Jessica; Gort Paniello, Clara; Moncusí Moix, Anna; Rodríguez Jara, Fátima; García Hidalgo, María C.; Torres, Gerard; Vengoechea Aragoncillo, José Javier; Gómez Falguera, Silvia; Cabo Gambín, Ramón; Caballero, Jesús; Bermejo Martin, Jesús F.; Ceccato, Adrián; Fernández Barat, Laia; Ferrer, Ricard; García Gasulla, Dario; Menéndez, Rosario; Motos, Anna; Peñuelas, Oscar; Riera, Jordi; Torres, Antoni; Barbé Illa, Ferran; de Gonzalo Calvo, David (Frontiers Media, 2022)
      Background: The pathophysiology of COVID-19-related critical illness is not completely understood. Here, we analyzed the microRNA (miRNA) profile of bronchial aspirate (BAS) samples from COVID-19 and non-COVID-19 patients ...
    • Genomic Characterization of Host Factors Related to SARS-CoV-2 Infection in People with Dementia and Control Populations: The GR@ACE/DEGESCO Study 

      de Rojas, Itziar; Hernández, Isabel; Montrreal, Laura; Quintela, Inés; Calero, Miguel; Royo, Jose Luís; Huerto Vilas, Raquel; González Pérez, Antonio; Franco Macías, Emilio; Macías, Juan; Menéndez González, Manuel; Frank García, Ana; Diez Fairen, Mónica; Lage, Carmen; García Madrona, Sebastián; Aguilera, Nuria; García González, Pablo; Puerta, Raquel; Sotolongo Grau, Oscar; Alonso Lana, Silvia; Rábano, Alberto; Arias Pastor, Alfonso; Pastor, Ana Belén; Corma Gómez, Anaïs; Martín Montes, Ángel; Martínez Rodríguez, Carmen; Buiza Rueda, Dolores; Rodríguez Rodríguez, Eloy; Álvarez, Ignacio; Rosas Allende, Irene; Pineda, Juan A.; Bernal Sánchez-Arjona, María; Fernández Fuertes, Marta; Mendoza, Silvia; Del Ser, Teodoro; García Ribas, Guillermo; Sánchez Juan, Pascual; Pastor, Pau; Bullido, María J.; Álvarez, Victoria; Real, Luis M; Mir, Pablo; Piñol Ripoll, Gerard; García Alberca, Jose María; Medina, Miguel; Orellana, Adelina; Butler, Chris R.; Marquié, Marta; Sáez, María Eugenia; Carracedo, Angel; Tárraga, Lluís; Boada, Mercè; Ruiz, Agustín (MDPI, 2021)
      Emerging studies have suggested several chromosomal regions as potential host genetic factors involved in the susceptibility to SARS-CoV-2 infection and disease outcome. We nested a COVID-19 genome-wide association study ...
    • Hacia el control de la COVID-19 a través de la vacunación: obstáculos, desafíos y oportunidades. Informe SESPAS 2022 

      Godoy i García, Pere; Castilla, Jesús; Astray, Jenaro; Godoy, Sofía; Tuells, José; Barrabeig i Fabregat, Irene; Domínguez García, Àngela (Elsevier, 2022)
      En España se inició el programa de vacunación en un contexto de alta transmisión y baja disponibilidad de vacunas. El objetivo de este artículo es revisar el programa de vacunación frente a la COVID-19 (3-3-2022) y valorar ...
    • Higher frequency of comorbidities in fully vaccinated patients admitted to the ICU due to severe COVID-19: a prospective, multicentre, observational study 

      Motos, Anna; López Gavín, Alexandre; Riera, Jordi; Ceccato, Adrián; Fernández Barat, Laia; Bermejo Martin, Jesús F.; Ferrer, Ricard; de Gonzalo Calvo, David; Menéndez, Rosario; Pérez Arnal, Raquel; García Gasulla, Dario; Rodríguez, Alejandro; Peñuelas, Oscar; Lorente, José Ángel; Almansa, Raquel; Gabarrús, Albert; Marin Corral, Judith; Ricart, Pilar; Roche Campo, Ferran; Sancho Chinesta, Susana; Socias, Lorenzo; Barbé Illa, Ferran; Torres, Antoni (European Respiratory Society, 2022)
      Severe COVID-19 disease requiring ICU admission is possible in the fully vaccinated population, especially in those with immunocompromised status and other comorbidities. Interventions to improve vaccine response might be ...
    • ICU-Acquired Pneumonia Is Associated with Poor HealthPost-COVID-19 Syndrome 

      Martín Loeches, Ignacio; Motos, Anna; Menéndez, Rosario; Gabarrús, Albert; González, Jessica; Fernández Barat, Laia; Ceccato, Adrián; Pérez Arnal, Raquel; García Gasulla, Dario; Ferrer, Ricard; Riera, Jordi; Lorente, José Ángel; Peñuelas, Oscar; Bermejo Martin, Jesús F.; de Gonzalo Calvo, David; Rodríguez, Alejandro; Barbé Illa, Ferran; Aguilera, Luciano; Amaya Villar, Rosario; Barberà, Carme; Barberán, José; Blandino Ortiz, Aaron; Bustamante Munguira, Elena; Caballero, Jesús; Carbajales, Cristina; Carbonell, Nieves; Catalán González, Mercedes; Galbán, Cristóbal; Gumucio Sanguino, Víctor D.; de la Torre, Maria del Carmen; Díaz, Emili; Gallego, Elena; García Garmendia, José Luis; Garnacho Montero, José; Gómez, José Manuel; Jorge García, Ruth Noemí; Loza Vázquez, Ana; Marin Corral, Judith; Martínez de la Gándara, Amalia; Martínez Varela, Ignacio; López Messa, Juan; Albaiceta, Guillermo M.; Novo, Mariana Andrea; Peñasco, Yhivian; Ricart, Pilar; Urrelo Cerrón, Luis; Sánchez Miralles, Angel; Sancho Chinesta, Susana; Socias, Lorenzo; Solé Violan, Jordi; Tamayo Lomas, Luis; Vidal, Pablo; Torres, Antoni (MDPI, 2021)
      Background. Some patients previously presenting with COVID-19 have been reported to develop persistent COVID-19 symptoms. While this information has been adequately recognised and extensively published with respect to ...
    • Impact on polytrauma patient prehospital care during the first wave of the COVID‑19 pandemic: a cross‑sectional study 

      Solà, Silvia; Yuguero Torres, Oriol; Roig, Guillermo; Prieto Arruñada, José Antonio; Español, Jaume; Morales Álvarez, Jorge; Muñoz, Manuel; Verge, Juan José; Jiménez Fàbrega, Xavier (Springer, 2021)
      Background The extraordinary situation caused by the onset of COVID-19 has meant that at prehospital level, the number of treatments, profle and time taken to respond for treating time-dependent pathologies has been greatly ...
    • Lack of protective effect of chloroquine derivatives on COVID-19 disease in a Spanish sample of chronically treated patients 

      Laplana Lafaja, Marina; Yuguero Torres, Oriol; Fibla Palazón, Joan (Public Library of Science, 2020)
      Background The search for a SARS-CoV-2 treatment has emerged as a worldwide priority. We evaluated the role of chloroquine and its derivatives in COVID-19 in Spanish individuals. Methods We performed a survey addressed ...
    • Lack of protective effect of chloroquine derivatives on COVID-19 disease in a Spanish sample of chronically treated patients 

      Laplana Lafaja, Marina; Yuguero Torres, Oriol; Fibla Palazón, Joan (2020)
      Background The search for a SARS-CoV-2 treatment has emerged as a worldwide priority. We evaluated the role of chloroquine and its derivatives in COVID-19 in Spanish individuals. Methods We performed a survey addressed ...
    • The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients 

      Torres, Antoni; Motos, Anna; Riera, Jordi; Fernández Barat, Laia; Ceccato, Adrián; Pérez Arnal, Raquel; García Gasulla, Dario; Peñuelas, Oscar; Lorente, José Ángel; Rodríguez, Alejandro; de Gonzalo Calvo, David; Almansa, Raquel; Gabarrús, Albert; Menéndez, Rosario; Bermejo Martin, Jesús F.; Ferrer, Ricard; Amaya Villar, Rosario; Añón, José M.; Barberà, Carme; Barberán, José; Blandino Ortiz, Aaron; Bustamante Munguira, Elena; Caballero, Jesús; Carbajales, Cristina; Carbonell, Nieves; Catalán González, Mercedes; Galbán, Cristóbal; Gumucio Sanguino, Víctor D.; de la Torre, Maria del Carmen; Díaz, Emili; Estella, Ángel; Gallego, Elena; García Garmendia, José Luis; Garnacho Montero, José; Gómez, José Manuel; Huerta, Arturo; Jorge García, Ruth Noemí; Loza Vázquez, Ana; Marin Corral, Judith; Martínez de la Gándara, Amalia; Martínez Varela, Ignacio; López Messa, Juan; Albaiceta, Guillermo M.; Novo, Mariana Andrea; Peñasco, Yhivian; Pozo Laderas, Juan Carlos; Ricart, Pilar; Salvador Adell, Inmaculada; Sánchez Miralles, Angel; Sancho Chinesta, Susana; Socias, Lorenzo; Solé Violan, Jordi; Suares Sipmann, Fernando; Tamayo Lomas, Luis; Trenado, José; Barbé Illa, Ferran (BMC; International Symposium on Intensive Care and Emergency Medicine (ISICEM); Critical Care Canada Forum (CCCF), 2021)
      Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three ...
    • Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID‑19 

      Bermejo Martin, Jesús F.; González Rivera, Milagros; Almansa, Raquel; Micheloud, Dariela; Tedim, Ana P.; Domínguez Gil, Marta; Resino, Salvador; Martín Fernández, Marta; Murua, Pablo Ryan; Pérez García, Felipe; Tamayo Lomas, Luis; López Izquierdo, Raúl; Bustamante Munguira, Elena; Aldecoa, César; Gómez, José Manuel; Rico Feijoo, Jesús; Orduña, Antonio; Méndez, Raúl; Fernández Natal, Isabel; Megías, Gregoria; González Estecha, Montserrat; Carriedo, Demetrio; Doncel, Cristina; Jorge, Noelia; Ortega, Alicia; Fuente, Amanda de la; Campo, Félix del; Fernández Ratero, José Antonio; Trapiello, Wysali; González Jiménez, Paula; Ruiz, Guadalupe; Kelvin, Alyson A.; Toloue Ostadgavahi, Ali; Oneizat, Ruth; Ruiz, Luz María; Miguéns, Iria; Gargallo, Esther; Muñoz, Ioana; Pelegrin, Sara; Martín, Silvia; García Olivares, Pablo; Cedeño, Jamil Antonio; Ruiz Albi, Tomás; Puertas, Carolina; Berezo, Jose Ángel; Renedo, Gloria; Herrán, Rubén; Bustamante Munguira, Juan; Enríquez, Pedro; Cicuendez, Ramón; Blanco, Jesús; Abadia, Jesica; Gómez Barquero, Julia; Mamolar, Nuria; Blanca López, Natalia; Valdivia, Luis Jorge; Fernández Caso, Belén; Mantecón, María Ángeles; Motos, Anna; Fernandez Barat, Laia; Ferrer, Ricard; Barbé Illa, Ferran; Torres, Antoni; Menéndez, Rosario; Eiros, José María; Kelvin, David J. (BMC, 2020)
      Background. COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host ...