Browsing Articles publicats (IRBLleida) by Subject "Fatty acid unsaturation"
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Exceptional human longevity is associated with a specific plasma phenotype of ether lipids
(Elsevier, 2019)A lipid profile resistant to oxidative damage is an inherent trait associated with animal lifespan. However, there is a lack of lipidomic studies on human longevity. Here we use mass spectrometry based technologies to ... -
Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behaviour, without changing mice longevity.
(Wiley Open Access; Anatomical Society of Great Britain and Ireland, 2014)The membrane fatty acid unsaturation hypothesis of aging and longevity is experimentally tested for the first time in mammals. Lifelong treatment of mice with the b1-blocker atenolol increased the amount of the ...