Browsing Articles publicats (IRBLleida) by Subject "Entorhinal cortex"

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Mitochondrial ATP-Synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology

Terni, Beatrice; Boada Pallàs, Jordi; Portero Otín, Manuel; Pamplona Gras, Reinald; Ferrer, Isidre (Wiley, 2010)

Oxidative stress has been implicated in the pathogenesis of several neurodegenerative diseases including Alzheimer's disease (AD). Several proteins have been identified as targets of oxidative damage in AD dementia (usually ...
The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer's Disease Pathology

Jové Font, Mariona; Mota Martorell, Natàlia; Torres Cabestany, Pascual; Ayala Jové, Ma. Victoria (Maria Victoria); Portero Otín, Manuel; Ferrer, Isidre; Pamplona Gras, Reinald (MDPI, 2021)

Current shreds of evidence point to the entorhinal cortex (EC) as the origin of the Alzheimer’s disease (AD) pathology in the cerebrum. Compared with other cortical areas, the neurons from this brain region possess an ...