Browsing Articles publicats (IRBLleida) by Subject "β-catenin"

Now showing items 1-2 of 2

Dickkopf-1 Inhibition Reactivates Wnt/beta-Catenin Signaling in Rhabdomyosarcoma, Induces Myogenic Markers In Vitro and Impairs Tumor Cell Survival In Vivo

Giralt, Irina; Gallo Oller, Gabriel; Navarro, Natalia; Zarzosa, Patricia; Pons, Guillem; Magdaleno, Ainara; Segura, Miguel F.; Sabado, Constantino; Hladun, Raquel; Arango, Diego; Sánchez de Toledo, José; Moreno, Lucas; Gallego, Soledad; Roma, Josep (MDPI, 2021)

The Wnt/β-catenin signaling pathway plays a pivotal role during embryogenesis and its deregulation is a key mechanism in the origin and progression of several tumors. Wnt antagonists have been described as key modulators ...
Signalling by neurotrophins and hepatocyte growth factor regulates axon morphogenesis by differential β-catenin phosphorylation

David, Mónica Delia; Yeramian Hakim, Andree; Duñach, Mireia; Llovera i Tomàs, Marta; Cantí Nicolás, Carles; Garcia de Herreros, Antonio; Comella i Carnicé, Joan Xavier; Herreros Danés, Judit (Company of Biologist, 2008)

Tyrosine phosphorylation of ß-catenin, a component of adhesion complexes and the Wnt pathway, affects cell adhesion, migration and gene transcription. By reducing ßcatenin availability using shRNA-mediated gene silencing ...