Now showing items 1-3 of 3

    • ARID1A-deficient cells require HDAC6 for progression of endometrial carcinoma 

      Megino-Luque, Cristina; Sisó, Pol; Mota Martorell, Natàlia; Navaridas Fernández de Bobadilla, Raúl; de la Rosa, Inés; Urdanibia, Izaskun; Albertí Valls, Manel; Santacana Espasa, Maria; Pinyol, Miquel; Bonifaci, Núria; Macià Armengol, Anna; Llobet Navàs, David; Gatius Calderó, Sònia; Matias-Guiu, Xavier; Eritja Sánchez, Núria (Federation of European Biochemical Societies; John Wiley & Sons, 2022)
      AT-rich interactive domain-containing protein 1A (ARID1A) loss-of-function mutation accompanied by a loss of ARID1A protein expression is frequently observed in endometrial carcinomas. However, the molecular mechanisms ...
    • BRAFV600E Mutant Allele Frequency (MAF) Influences Melanoma Clinicopathologic Characteristics 

      Soria, Xavier; Vilardell, Felip; Maiques Carlos, Oscar; Barceló Gómez, Carla; Sisó, Pol; de la Rosa, Inés; Velasco Sánchez, Ana; Cuevas Sánchez, Dolors; Santacana Espasa, Maria; Gatius Calderó, Sònia; Matias-Guiu, Xavier; Rodrigo, Alberto; Macià Armengol, Anna; Martí Laborda, Rosa Ma. (MDPI, 2021)
      Background: Cutaneous melanoma shows high variability regarding clinicopathological presentation, evolution and prognosis. Methods: Next generation sequencing was performed to analyze hotspot mutations in different areas ...
    • T-Type Calcium Channels: A Potential Novel Target in Melanoma 

      Barceló Gómez, Carla; Sisó, Pol; Maiques Carlos, Oscar; de la Rosa, Inés; Martí Laborda, Rosa Ma.; Macià Armengol, Anna (MDPI, 2020)
      T-type calcium channels (TTCCs) are overexpressed in several cancers. In this review, we summarize the recent advances and new insights into TTCC biology, tumor progression, and prognosis biomarker and therapeutic potential ...