Now showing items 1-9 of 9

    • Bronchial Aspirate-Based Profiling Identifies MicroRNA Signatures Associated With COVID-19 and Fatal Disease in Critically Ill Patients 

      Molinero, Marta; Benítez, Iván; González, Jessica; Gort Paniello, Clara; Moncusí Moix, Anna; Rodríguez Jara, Fátima; García Hidalgo, María C.; Torres, Gerard; Vengoechea Aragoncillo, José Javier; Gómez Falguera, Silvia; Cabo Gambín, Ramón; Caballero, Jesús; Bermejo Martin, Jesús F.; Ceccato, Adrián; Fernández Barat, Laia; Ferrer, Ricard; García Gasulla, Dario; Menéndez, Rosario; Motos, Anna; Peñuelas, Oscar; Riera, Jordi; Torres, Antoni; Barbé Illa, Ferran; de Gonzalo Calvo, David (Frontiers Media, 2022)
      Background: The pathophysiology of COVID-19-related critical illness is not completely understood. Here, we analyzed the microRNA (miRNA) profile of bronchial aspirate (BAS) samples from COVID-19 and non-COVID-19 patients ...
    • Clinical management and outcome differences between first and second waves among COVID-19 hospitalized patients: A regional prospective observational cohort 

      Zuil, María; Benítez, Iván; Cabo Gambín, Ramón; Manzano Senra, Carlos; Moncusí Moix, Anna; Gort Paniello, Clara; de Gonzalo Calvo, David; Molinero, Marta; Vengoechea Aragoncillo, José Javier; Comella, Thais; Batlle Garcia, Jordi de; Torres, Gerard; Torres, Antoni; Barbé Illa, Ferran; González, Jessica (Public Library of Science, 2021)
      The objective was to describe the clinical characteristics and outcomes of hospitalized COVID-19 patients during the two different epidemic periods. Prospective, observational, cohort study of hospitalized COVID-19. A total ...
    • Endogenous controls and microRNA profile in female patients with obstructive sleep apnea 

      Zapater, Andrea; Benítez, Iván; Santamaria-Martos, Fernando; Pinilla, Lucía; Targa, Adriano; de Gonzalo Calvo, David; Torres, Gerard; Minguez Roure, Olga; Cortijo, Anunciación; Dalmases, Mireia; Barbé Illa, Ferran; Sánchez de la Torre, Manuel (Nature Research, 2022)
      This work was supported by Instituto de Salud Carlos III (PI14/01266, PI18/00449, PI19/00907, PI20/00577), co-funded by FEDER, “Una manera de hacer europa”, IRBLleida – Fundació Dr. Pifarré, CERCA Programme/Generalitat de ...
    • Higher frequency of comorbidities in fully vaccinated patients admitted to the ICU due to severe COVID-19: a prospective, multicentre, observational study 

      Motos, Anna; López Gavín, Alexandre; Riera, Jordi; Ceccato, Adrián; Fernández Barat, Laia; Bermejo Martin, Jesús F.; Ferrer, Ricard; de Gonzalo Calvo, David; Menéndez, Rosario; Pérez Arnal, Raquel; García Gasulla, Dario; Rodríguez, Alejandro; Peñuelas, Oscar; Lorente, José Ángel; Almansa, Raquel; Gabarrús, Albert; Marin Corral, Judith; Ricart, Pilar; Roche Campo, Ferran; Sancho Chinesta, Susana; Socias, Lorenzo; Barbé Illa, Ferran; Torres, Antoni (European Respiratory Society, 2022)
      Severe COVID-19 disease requiring ICU admission is possible in the fully vaccinated population, especially in those with immunocompromised status and other comorbidities. Interventions to improve vaccine response might be ...
    • ICU-Acquired Pneumonia Is Associated with Poor HealthPost-COVID-19 Syndrome 

      Martín Loeches, Ignacio; Motos, Anna; Menéndez, Rosario; Gabarrús, Albert; González, Jessica; Fernández Barat, Laia; Ceccato, Adrián; Pérez Arnal, Raquel; García Gasulla, Dario; Ferrer, Ricard; Riera, Jordi; Lorente, José Ángel; Peñuelas, Oscar; Bermejo Martin, Jesús F.; de Gonzalo Calvo, David; Rodríguez, Alejandro; Barbé Illa, Ferran; Aguilera, Luciano; Amaya Villar, Rosario; Barberà, Carme; Barberán, José; Blandino Ortiz, Aaron; Bustamante Munguira, Elena; Caballero, Jesús; Carbajales, Cristina; Carbonell, Nieves; Catalán González, Mercedes; Galbán, Cristóbal; Gumucio Sanguino, Víctor D.; de la Torre, Maria del Carmen; Díaz, Emili; Gallego, Elena; García Garmendia, José Luis; Garnacho Montero, José; Gómez, José Manuel; Jorge García, Ruth Noemí; Loza Vázquez, Ana; Marin Corral, Judith; Martínez de la Gándara, Amalia; Martínez Varela, Ignacio; López Messa, Juan; Albaiceta, Guillermo M.; Novo, Mariana Andrea; Peñasco, Yhivian; Ricart, Pilar; Urrelo Cerrón, Luis; Sánchez Miralles, Angel; Sancho Chinesta, Susana; Socias, Lorenzo; Solé Violan, Jordi; Tamayo Lomas, Luis; Vidal, Pablo; Torres, Antoni (MDPI, 2021)
      Background. Some patients previously presenting with COVID-19 have been reported to develop persistent COVID-19 symptoms. While this information has been adequately recognised and extensively published with respect to ...
    • Identification and validation of endogenous control miRNAs in plasma samples for normalization of qPCR data for Alzheimer's disease 

      Dakterzada, Farida; Targa, Adriano; Benítez, Iván; Romero El Khayat, Leila; de Gonzalo Calvo, David; Torres, Gerard; Moncusí Moix, Anna; Huerto Vilas, Raquel; Sánchez de la Torre, Manuel; Barbé Illa, Ferran; Piñol Ripoll, Gerard (BCM, 2020)
      Background. MicroRNAs (miRNAs) are noncoding RNAs that are highly relevant as disease biomarkers. Several studies that explored the role of miRNAs in Alzheimer’s disease (AD) demonstrated their usefulness in clinical ...
    • Impact of time to intubation on mortality and pulmonary sequelae in critically ill patients with COVID-19: a prospective cohort study 

      González, Jessica; Benítez, Iván; de Gonzalo Calvo, David; Torres, Gerard; Batlle Garcia, Jordi de; Gómez Falguera, Silvia; Moncusí Moix, Anna; Carmona, Paola; Santisteve, Sally; Monge Esqué, Aida; Gort Paniello, Clara; Zuil, María; Cabo Gambín, Ramón; Manzano Senra, Carlos; Vengoechea Aragoncillo, José Javier; Vaca, Rafaela; Minguez Roure, Olga; Aguilar, María; Ferrer, Ricard; Ceccato, Adrián; Fernández Barat, Laia; Motos, Anna; Riera, Jordi; Menéndez, Rosario; García Gasulla, Dario; Peñuelas, Oscar; Labarca Trucios, Gonzalo; Caballero, Jesús; Barberà, Carme; Torres, Antoni; Barbé Illa, Ferran (BCM, 2022)
      Question: We evaluated whether the time between first respiratory support and intubation of patients receiving invasive mechanical ventilation (IMV) due to COVID-19 was associated with mortality or pulmonary sequelae. Materials ...
    • Reduced Levels of miR-342-5p in Plasma Are Associated With Worse Cognitive Evolution in Patients With Mild Alzheimer’s Disease 

      Dakterzada, Farida; Benítez, Iván; Targa, Adriano; Lladó, Albert; Torres, Gerard; Romero, Leila; de Gonzalo Calvo, David; Moncusí Moix, Anna; Tort Merino, Adrià; Huerto Vilas, Raquel; Sánchez de la Torre, Manuel; Barbé Illa, Ferran; Piñol Ripoll, Gerard (Frontiers Media, 2021)
      Background: Progressive cognitive decline is the most relevant clinical symptom of Alzheimer’s disease (AD). However, the rate of cognitive decline is highly variable between patients. Synaptic deficits are the neuropathological ...
    • The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients 

      Torres, Antoni; Motos, Anna; Riera, Jordi; Fernández Barat, Laia; Ceccato, Adrián; Pérez Arnal, Raquel; García Gasulla, Dario; Peñuelas, Oscar; Lorente, José Ángel; Rodríguez, Alejandro; de Gonzalo Calvo, David; Almansa, Raquel; Gabarrús, Albert; Menéndez, Rosario; Bermejo Martin, Jesús F.; Ferrer, Ricard; Amaya Villar, Rosario; Añón, José M.; Barberà, Carme; Barberán, José; Blandino Ortiz, Aaron; Bustamante Munguira, Elena; Caballero, Jesús; Carbajales, Cristina; Carbonell, Nieves; Catalán González, Mercedes; Galbán, Cristóbal; Gumucio Sanguino, Víctor D.; de la Torre, Maria del Carmen; Díaz, Emili; Estella, Ángel; Gallego, Elena; García Garmendia, José Luis; Garnacho Montero, José; Gómez, José Manuel; Huerta, Arturo; Jorge García, Ruth Noemí; Loza Vázquez, Ana; Marin Corral, Judith; Martínez de la Gándara, Amalia; Martínez Varela, Ignacio; López Messa, Juan; Albaiceta, Guillermo M.; Novo, Mariana Andrea; Peñasco, Yhivian; Pozo Laderas, Juan Carlos; Ricart, Pilar; Salvador Adell, Inmaculada; Sánchez Miralles, Angel; Sancho Chinesta, Susana; Socias, Lorenzo; Solé Violan, Jordi; Suares Sipmann, Fernando; Tamayo Lomas, Luis; Trenado, José; Barbé Illa, Ferran (BMC; International Symposium on Intensive Care and Emergency Medicine (ISICEM); Critical Care Canada Forum (CCCF), 2021)
      Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three ...