Now showing items 1-3 of 3

    • Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks 

      Zapatka, Mariel; Pociño Merino, Irene; Heluani-Gahete, Hayat; Bermúdez López, Marcelino; Tarrés, Marc; Ibars Estiarte, Eva Irene; Solé-Soler, Roger; Gutiérrez-Escribano, Pilar; Apostolova, Sonia; Casas Herranz, Celia; Aragon, Luis; Wellinger, Ralf Erik; Colomina i Gabarrella, Neus; Torres Rosell, Jordi (Elsevier, 2019)
      Replication of a damaged DNA template can threaten the integrity of the genome, requiring the use of various mechanisms to tolerate DNA lesions. The Smc5/6 complex, together with the Nse2/Mms21 SUMO ligase, plays essential ...
    • Yeast as a model system to study metabolic impact of selenium compounds 

      Herrero Perpiñán, Enrique; Wellinger, Ralf Erik (Shared Science Publishers, 2015)
      Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces cerevisiae cells, which constitute an adequate model to study such toxicity at the molecular level ...
    • Zim17/Tim15 links mitochondrial iron–sulfur cluster biosynthesis to nuclear genome stability 

      Díaz de la Loza, María del Carmen; Gallardo, Mercedes; García-Rubio, María Luisa; Izquierdo, Alicia; Herrero Perpiñán, Enrique; Aguilera, Andrés; Wellinger, Ralf Erik (Oxford University Press, 2011)
      Genomic instability is related to a wide-range of human diseases. Here, we show that mitochondrial iron–sulfur cluster biosynthesis is important for the maintenance of nuclear genome stability in Saccharomyces cerevisiae. ...