Now showing items 1-3 of 3

    • Clonal relationship and directionality of progression of synchronous endometrial and ovarian carcinomas in patients with DNA mismatch repair-deficiency associated syndromes 

      Moukarzel, Lea A.; Cruz Paula, Arnaud Da; Ferrando, Lorenzo; Hoang, Timothy; Martins Sebastiao, Ana Paula; Pareja, Fresia; Park, Kay J.; Jungbluth, Achim A; Capellà, Gabriel; Pineda, Marta; Levin, Jeffrey D.; Abu-Rustum, Nadeem R.; Ellenson, Lora H.; Vidal Bel, August; Reis-Filho, Jorge S.; Matias-Guiu, Xavier; Cadoo, Karen; Stadler, Zsofia K.; Weigelt, Britta (Springer Nature; United States and Canadian Academy of Pathology (USCAP), 2021)
      Sporadic synchronous endometrial (ECs) and ovarian cancers (OCs), although clinically considered to be independent primaries, have been shown to be clonally related and likely constitute metastases from each other. We ...
    • Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary 

      Gatius Calderó, Sònia; Cruz Paula, Arnaud Da; Silva, Edaise M. da; Segura, Sheila E.; Pareja, Fresia; Bi, Rui; Selenica, Pier; Kim, Sarah H.; Ferrando, Lorenzo; Vahdatinia, Mahsa; Soslow, Robert A.; Vidal, August; Przybycin, Christopher G.; Abu-Rustum, Nadeem R.; Matias-Guiu, Xavier; Rubin, Brian P.; Reis-Filho, Jorge S.; DeLair, Deborah F.; Weigelt, Britta (2020)
      Adult-type granulosa cell tumor (aGCT) is a rare malignant ovarian sex cord-stromal tumor, harboring recurrent FOXL2 c.C402G/p.C134W hotspot mutations in 97% of cases. These tumors are considered to have a favorable ...
    • Intratumor genetic heterogeneity and clonal evolution to decode endometrial cancer progression 

      Mota, Alba; Oltra, Sara S.; Selenica, Pier; Moiola, Cristian P.; Casas Arozamena, Carlos; López-Gil, Carlos; Díaz, Eva; Gatius Calderó, Sònia; Ruiz Miró, Maria; Calvo, Ana; Rojo Sebastián, Alejandro; Hurtado, Pablo; Piñeiro, Roberto; Colás, Eva; Gil-Moreno, Antonio; Reis-Filho, Jorge S.; Muinelo-Romay, Laura; Abal, Miguel; Matias-Guiu, Xavier; Weigelt, Britta; Moreno Bueno, Gema (Springer Nature, 2022)
      Analyzing different tumor regions by next generation sequencing allows the assessment of intratumor genetic heterogeneity (ITGH), a phenomenon that has been studied widely in some tumor types but has been less well explored ...