Browsing Articles publicats (IRBLleida) by Author "Saavedra Ávila, Noemí Alejandra"

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CDK11 promotes cytokine-induced apoptosis in pancreatic beta cells independently of glucose concentration and is regulated by inflammation in the NOD mouse model

Sala Solé, Ester; Vived Maza, Celia; Luna Salinas, Júlia; Saavedra Ávila, Noemí Alejandra; Sengupta, Upasana; Castaño, A. Raúl; Villar-Pazos, Sabrina; Haba, Laura; Verdaguer Autonell, Joan; Ropero, Ana Belén; Stratmann, Thomas; Pizarro, Javier; Vázquez-Carrera, Manuel; Nadal, Ángel; Lahti, Jill M.; Mora Giral, Concepció (Frontiers, 2021-02-10)

Background: Pancreatic islets are exposed to strong pro-apoptotic stimuli: inflammation and hyperglycemia, during the progression of the autoimmune diabetes (T1D). We found that the Cdk11(Cyclin Dependent Kinase 11) is ...