Now showing items 1-7 of 7

    • Association of FGF-2 Concentrations with Atheroma Progression in Chronic Kidney Disease Patients 

      Bozić Stanojević, Milica; Betriu i Bars, M. Àngels; Bermúdez López, Marcelino; Ortiz, Alberto; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (American Society of Nephrology, 2018)
      Background and objectives: Atherosclerosis is highly prevalent in CKD. The rate of progression of atherosclerosis is associated with cardiovascular events. Fibroblast growth factor 2 (FGF-2) is a member of the FGF family ...
    • Could IL-17A be a novel therapeutic target in diabetic nephropathy? 

      Lavoz, Carolina; Rayego Mateos, Sandra; Orejudo, Macarena; Opazo Rios, Lucas; Marchant, Vanessa; Marquez Exposito, Laura; Tejera Muñoz, Antonio; Navarro González, Juan F.; Droguett, Alejandra; Ortiz, Alberto; Egido, Jesús; Mezzano, Sergio; Rodrigues-Diez, Raul; Ruiz-Ortega, Marta (MDPI, 2020)
      Chronic kidney disease has become a major medical issue in recent years due to its high prevalence worldwide, its association with premature mortality, and its social and economic implications. A number of patients gradually ...
    • Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis 

      Marquez Exposito, Laura; Lavoz, Carolina; Rodrigues-Diez, Raul; Rayego Mateos, Sandra; Orejudo, Macarena; Cantero-Navarro, Elena; Ortiz, Alberto; Egido, Jesús; Selgas, Rafael; Mezzano, Sergio; Ruiz-Ortega, Marta (Frontiers Media, 2018)
      Chronic kidney disease (CKD) is emerging as an important health problem due to the increase number of CKD patients and the absence of an effective curative treatment. Gremlin has been proposed as a novel therapeutic target ...
    • Impaired Vitamin D Signaling in Endothelial Cell Leads to an Enhanced Leukocyte-Endothelium Interplay: Implications for Atherosclerosis Development 

      Dolcet Roca, Xavier; Encinas Martín, Mario; Bozić Stanojević, Milica; Álvarez, Ángeles; Pablo, Carmen de; Sanchez-Niño, Maria-Dolores; Ortiz, Alberto; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (Public Library of Science, 2015)
      Endothelial cell activation leading to leukocyte recruitment and adhesion plays an essential role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective actions, while its deficiency is a risk ...
    • Lipid management in patients with chronic kidney disease 

      Ferro, Charles J.; Mark, Patrick B.; Kanbay, Mehmet; Sarafidis, Pantelis; Heine, Gunnar H.; Rossignol, Patrick; Massy, Ziad A.; Mallamaci, Francesca; Valdivielso Revilla, José Manuel; Malyszko, Jolanta; Verhaar, Marianne C.; Ekart, Robert; Vanholder, Raymond; London, Gerard; Ortiz, Alberto; Zoccali, Carmine (Nature Research, 2018)
      An increased risk of cardiovascular disease, independent of conventional risk factors, is present even at minor levels of renal impairment and is highest in patients with end-stage renal disease (ESRD) requiring dialysis. ...
    • Paricalcitol Inhibits Aldosterone-Induced Proinflammatory Factors by Modulating Epidermal Growth Factor Receptor Pathway in Cultured Tubular Epithelial Cells 

      Morgado-Pascual, José L.; Rayego Mateos, Sandra; Valdivielso Revilla, José Manuel; Ortiz, Alberto; Egido, Jesús; Ruiz-Ortega, Marta (Hindawi Publishing Corporation, 2015)
      Chronic kidney disease is characterized by Vitamin D deficiency and activation of the renin-angiotensin-aldosterone system. Increasing data show that vitamin D receptor agonists (VDRAs) exert beneficial effects in renal ...
    • The Spanish Society of Nephrology (SENEFRO) commentary to the Spain GBD 2016 report: Keeping chronic kidney disease out of sight of health authorities will only magnify the problem 

      Ortiz, Alberto; Sanchez-Niño, Maria-Dolores; Crespo-Barrio, Marta; De-Sequera-Ortiz, Patricia; Fernández i Giráldez, Elvira; García-Maset, Rafael; Macía-Heras, Manuel; Pérez Fontán, Miguel; Rodríguez, Mariano; Salgueira-Lazo, Mercedes; Sánchez Alvarez, Emilio; Santamaría-Olmo, Rafael; Simal-Blanco, Fernando; Pino, María Dolores del (Elsevier, 2019)
      The Global Burden of Disease (GBD) study measures the health of populations worldwide and by country on an annual basis and aims at helping guide public policy on health issues. The GBD estimates for Spain in 2016 and ...