Now showing items 1-2 of 2

    • Intermittent Hypoxia Is Associated With High Hypoxia Inducible Factor-1α but Not High Vascular Endothelial Growth Factor Cell Expression in Tumors of Cutaneous Melanoma Patients 

      Almendros, Isaac; Martínez-García, Miguel Angel; Campos-Rodríguez, Francisco; Riveiro-Falkenbach, Erica; Rodríguez-Peralto, José L.; Nagore, Eduardo; Martorell-Calatayud, Antonio; Hernández Blasco, Luis; Bañuls Roca, Jose; Chiner, Eusebi; Sánchez de la Torre, Alicia; Abad, Jorge; Montserrat, Josep Maria; Pérez-Gil, Amalia; Cabriada, Valentín; Cano-Pumarega, Irene; Corral-Peñafiel, Jaime; Diaz-Cambriles, Trinidad; Mediano, Olga; Dalmau-Arias, Joan; Farré, Ramon; Gozal, David; Spanish Sleep Network (Frontiers Media, 2018)
      Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced ...
    • Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma 

      Cubillos‑Zapata, Carolina; Martínez‑García, Miguel Ángel; Díaz‑García, Elena; Jaureguizar, Ana; Campos‑Rodríguez, Francisco; Sánchez de la Torre, Manuel; Nagore, Eduardo; Martorell‑Calatayud, Antonio; Hernández Blasco, Luis; Pastor, Esther; Abad, Jorge; Montserrat, Josep Maria; Cabriada‑Nuño, Valentín; Cano‑Pumarega, Irene; Corral-Peñafiel, Jaime; Arias, Eva; Mediano, Olga; Somoza, María; Dalmau-Arias, Joan; Almendros, Isaac; Farré, Ramon; López‑Collazo, Eduardo; Gozal, David; García Río, Francisco (Nature Research, 2020)
      Active transforming growth factor-β1 (TGF-β1), a cytokine partially regulated by hypoxia and obesity, has been related with poor prognosis in several tumors. We determine whether obstructive sleep apnea (OSA) increases ...