Browsing Articles publicats (IRBLleida) by Author "Mate, Ianire"

Now showing items 1-1 of 1

Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behaviour, without changing mice longevity.

Pamplona Gras, Reinald; Portero Otín, Manuel; Naudí i Farré, Alba; Fuente, Monica de la; Barja, Gustavo; López Torres, Mónica; Mate, Ianire; Cruces, Julia; Gómez, José; Sánchez-Roman, Ines; Gómez Rodríguez, Alexia (Wiley Open Access; Anatomical Society of Great Britain and Ireland, 2014)

The membrane fatty acid unsaturation hypothesis of aging and longevity is experimentally tested for the first time in mammals. Lifelong treatment of mice with the b1-blocker atenolol increased the amount of the ...