Now showing items 1-7 of 7

    • Addition of IMP3 to L1CAM for discrimination between low- and high-grade endometrial carcinomas: a European Network for Individualised Treatment of Endometrial Cancer collaboration study 

      Visser, Nicole C.M.; van der Putten, Louis J. M.; van Egerschot, Alex; van de Vijver, Koen; Santacana Espasa, Maria; Bronsert, Peter; Hirschfeld, Marc; Colás, Eva; Colás, Eva; Gil-Moreno, Antonio; Garcia, Angel; Mancebo, Gemma; Alameda, Fransesc; Krakstad, Camilla; Tangen, Ingvild L.; Huvila, Jutta; Schrauwen, Stefanie; Koskas, Martin; Walker, Francine; Weinberger, Vit; Minar, Lubos; Hausnerova, Jitka; Snijders, Marc P. L. M.; van den Berg-van Erp, Saskia; Matias-Guiu, Xavier; Trovik, Jone; Amant, Frederic; Massuger, Leon F. A. G.; Bulten, Johan; Pijnenborg, Johanna M. A. (Elsevier, 2019)
      Discrimination between low- and high-grade endometrial carcinomas (ECs) is clinically relevant but can be challenging for pathologists, with moderate interobserver agreement. Insulin-like growth factor-II mRNA-binding ...
    • Immunohistochemical biomarkers are prognostic relevant in addition to the ESMO-ESGO-ESTRO risk classification in endometrial cancer 

      Vrede, S. W.; Van Weelden, Willem Jan; Visser, N. C. M.; Bulten, Johan; van der Putten, Louis J. M.; van de Vijver, Koen; Santacana, M.; Colas, L.; Gil-Moreno, Antonio; Moiola, Cristian P.; Mancebo, Gemma; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S.; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Bednarikova, M.; Hausnerova, Jitka; van der Wurff, Anneke A. M.; Matias-Guiu, Xavier; Amant, Frederic; ENITEC Consortium; Snijders, Marc P. L. M.; Küsters-Vandevelde, Heidi V. N; Reijnen, Casper; Pijnenborg, Johanna M. A. (Elsevier, 2021)
      Objective Pre-operative immunohistochemical (IHC) biomarkers are not incorporated in endometrial cancer (EC) risk classification. We aim to investigate the added prognostic relevance of IHC biomarkers to the ESMO-ESGO-ESTRO ...
    • L1CAM expression in uterine carcinosarcoma is limited to the epithelial component and may be involved in epithelial–mesenchymal transition 

      Versluis, MAC; Plat, A; de Bruyn, M; Matias-Guiu, Xavier; Trovik, Jone; Krakstad, Camilla; Nijman, Hans W.; Bosse, Tjalling; de Bock, GH; Hollema, H (Springer Verlag, 2018)
      Uterine carcinosarcoma (UCS) has been proposed as a model for epithelial–mesenchymal transition (EMT), a process characterized by a functional change facilitating migration and metastasis in many types of cancer. L1CAMis ...
    • Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer 

      Alonso-Alconada, Lorena; Muinelo-Romay, Laura; Madissoo, Kadri; Díaz-López, Antonio; Krakstad, Camilla; Trovik, Jone; Wik, Elisabeth; Hapangama, Dharani; Coenegrachts, Lieve; Cano, Amparo; Gil-Moreno, Antonio; Chiva, Luís; Cueva, Juan; Vieito, María; Ortega Izquierdo, Maria Eugenia; Mariscal, Javier; Colás, Eva; Castellví, Josep; Cusido, Maite; Dolcet Roca, Xavier; Nijman, Hans W.; Bosse, Tjalling; Green, John A.; Romano, Andrea; Reventós, Jaume; López-López, Rafael; Salvesen, Helga B.; Amant, Frederic; Matias-Guiu, Xavier; Moreno-Bueno, Gema; Abal, Miguel (Biomed Central, 2014)
      Background: About 20% of patients diagnosed with endometrial cancer (EC) are considered high-risk with unfavorable prognosis. In the framework of the European Network for Individualized Treatment in EC (ENITEC), we ...
    • Patient-Derived Xenograft Models for Endometrial Cancer Research 

      Moiola, Cristian P.; Lopez-Gil, Carlos; Cabrera, Silvia; Garcia, Angel; Van Nyen, Tom; Annibali, Daniela; Fonnes, Tina; Vidal, August; Villanueva, Alberto; Matias-Guiu, Xavier; Krakstad, Camilla; Amant, Frederic; Gil-Moreno, Antonio; Colás, Eva (MDPI, 2018)
      Endometrial cancer (EC) is the most common malignancy of the genital tract among women in developed countries. Recently, a molecular classification of EC has been performed providing a system that, in conjunction with ...
    • Poor outcome in hypoxic endometrial carcinoma is related to vascular density 

      Reijnen, Casper; Van Weelden, Willem Jan; Arts, Martijn S. J. P.; Peters, Johan P.; Rijken, Paul F.; van de Vijver, Koen; Santacana Espasa, Maria; Bronsert, Peter; Bulten, Johan; Hirschfeld, Marc; Colás, Eva; Gil-Moreno, Antonio; Reques, Armando; Mancebo, Gemma; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Minar, Lubos; Jandakova, Eva; Snijders, Marc P. L. M.; van den Berg-van Erp, Saskia; Küsters-Vandevelde, Heidi V. N; Matias-Guiu, Xavier; Amant, Frederic; Massuger, Leon F. A. G.; Bussink, Johan; Pijnenborg, Johanna M. A. (Springer NatureCancer Research UK, 2019)
      BACKGROUND: Identification of endometrial carcinoma (EC) patients at high risk of recurrence is lacking. In this study, the prognostic role of hypoxia and angiogenesis was investigated in EC patients. METHODS: Tumour ...
    • Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients 

      Eritja Sánchez, Núria; Jové Font, Mariona; Eldevik Fasmer, Kristine; Gatius Calderó, Sònia; Portero Otín, Manuel; Trovik, Jone; Krakstad, Camilla; Sol, Joaquim; Pamplona Gras, Reinald; Haldorsen, Ingfrid S.; Matias-Guiu, Xavier (Impact Journals, 2017)
      Purpose: We aimed to study the potential influence of tumour blood flow –obtained from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)- in the metabolomic profiles of endometrial tumours. Methods: Liquid ...