Now showing items 1-15 of 15

    • Assessment of Inner Retinal Layers and Choroidal Thickness in Type 1 Diabetes Mellitus: A Cross-Sectional Study 

      Carbonell, Marc; Alonso, Núria; Castelblanco Echavarría, Esmeralda; Real, Jordi; Ramírez-Morros, Anna; Simó, Rafael; Hernández, Cristina; Jurjo Campo, Carmen; Traveset Maeso, Alicia; Valldeperas, Xavier; Mauricio Puente, Dídac (MDPI, 2019)
      Recent studies have shown that retinal neurodegeneration may precede visible vascular changes in diabetic retinopathy (DR). In addition, the relationship of choroidal thickness (CT) with DR stage is not well defined. To ...
    • Budget impact analysis of switching to digital mammography in a population-based breast cancer screening program: a discrete event simulation model 

      Comas, Mercè; Arrospide, Arantzazu; Mar, Javier; Sala i Serra, Maria; Vilaprinyo Terré, Ester; Hernández, Cristina; Cots, Francesc; Martínez, Juan; Castells, Xavier (Public Library of Science, 2014)
      Objective: To assess the budgetary impact of switching from screen-film mammography to full-field digital mammography in a population-based breast cancer screening program. Methods: A discrete-event simulation model was ...
    • Characteristics of atheromatosis in the prediabetes stage: a cross-sectional investigation of the Ilervas project 

      Sánchez Peña, Enric; Betriu i Bars, M. Àngels; López Cano, Carolina; Hernández García, Marta; Fernández i Giráldez, Elvira; Purroy Garcia, Francisco; Bermúdez López, Marcelino; Farràs-Sallés, Cristina; Barril, Silvia; Pamplona Gras, Reinald; Rius, Ferran; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (BioMed Central, 2019-11-15)
      BACKGROUND: Prediabetes has recently been associated with subclinical atheromatous disease in the middle-aged population. Our aim was to characterize atheromatous plaque burden by the number of affected territories and the ...
    • Characterization of sleep breathing pattern in patients with type 2 diabetes: sweet sleep study 

      Lecube Torelló, Albert; Sampol, Gabriel; Hernández, Cristina; Romero, Odile; Ciudin, Andreea; Simó, Rafael (Public Library of Science, 2015)
      Background: Although sleep apnea-hypopnea syndrome (SAHS) is highly prevalent in patients with type 2 diabetes (T2D), it is unknown whether or not subjects with and without T2D share the same sleep breathing pattern. ...
    • Effect of Glucose Improvement on Nocturnal Sleep Breathing Parameters in Patients with Type 2 Diabetes: The Candy Dreams Study 

      Gutiérrez Carrasquilla, Liliana; López Cano, Carolina; Sánchez Peña, Enric; Barbé Illa, Ferran; Dalmases, Mireia; Hernández García, Marta; Campos, Angela; Gaeta, Anna Michela; Carmona, Paola; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (MDPI, 2020)
      Type 2 diabetes exerts a negative impact on sleep breathing. It is unknown whether a long-term improvement in glycemic control ameliorates this effect. We conducted an interventional study with 35 patients with type 2 ...
    • Effect of Subcutaneous Insulin on Spirometric Maneuvers in Patients with Type 1 Diabetes: A Case-Control Study 

      Sánchez Peña, Enric; Mizab, Chadia; Sauret, Ariadna; Barbé Illa, Ferran; Martí, Raquel; López Cano, Carolina; Hernández García, Marta; Gutiérrez Carrasquilla, Liliana; Carmona, Paola; González, Jessica; Dalmases, Mireia; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (MDPI, 2020)
      In order to compare spirometric maneuvers in adults according to the presence of type 1 diabetes, a case-control study including 75 patients with type 1 diabetes and 75 controls matched by sex, age, and body mass index ...
    • Effect of Type 2 Diabetes Mellitus on the Hypoxia-Inducible Factor 1-Alpha Expression. Is There a Relationship with the Clock Genes? 

      López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Barbé Illa, Ferran; Sánchez Peña, Enric; Hernández García, Marta; Martí, Raquel; Ceperuelo-Mallafre, Vicky; Dalmases, Mireia; Fernández-Veledo, Sonia; Vendrell, Joan; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (MDPI, 2020)
      Limited reports exist on the relationships between regulation of oxygen homeostasis and circadian clock genes in type 2 diabetes. We examined whether the expression of Hypoxia-Inducible Factor-1α (HIF-1α) and HIF-2α ...
    • Genetic Testing to Predict Weight Loss and Diabetes Remission and Long-Term Sustainability after Bariatric Surgery: A Pilot Study 

      Ciudin, Andreea; Fidilio, Enzamaria; Ortiz, Angel; Pich, Sara; Salas, Eduardo; Mesa, Jordi; Hernández, Cristina; Simó-Servat, Olga; Lecube Torelló, Albert (MDPI, 2019)
      Introduction: The aim of this pilot study was to assess genetic predisposition risk scores (GPS) in type 2 diabetic and non-diabetic patients in order to predict the better response to bariatric surgery (BS) in terms of ...
    • Global assessment of the impact of type 2 diabetes on sleep through specific questionnaires. A case-control study 

      Lecube Torelló, Albert; Sánchez Peña, Enric; Gómez Peralta, Fernando; Abreu, Cristina; Valls Marsal, Joan; Mestre, Olga; Romero, Odile; Martínez González, María Dolores; Sampol, Gabriel; Ciudin, Andreea; Hernández, Cristina; Simó, Rafael (Public Library of Science, 2016)
      Type 2 diabetes (T2D) is an independent risk factor for sleep breathing disorders. However, it is unknown whether T2D affects daily somnolence and quality of sleep independently of the impairment of polysomnographic ...
    • Liraglutide Improves Forced Vital Capacity in Individuals With Type 2 Diabetes: Data From the Randomized Crossover LIRALUNG Study 

      López Cano, Carolina; Ciudin, Andreea; Sánchez Peña, Enric; Tinahones, Francisco José; Barbé Illa, Ferran; Dalmases, Mireia; García Ramírez, Marta; Soto, Alfonso; Michela Gaeta, Anna; Pellitero, Silvia; Martí, Raquel; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (American Diabetes Association, 2022)
      To evaluate the effect of liraglutide, a glucagon-like peptide 1 receptor agonist, on pulmonary function and serum levels of surfactant protein D (SP-D) in type 2 diabetes. A double-blind, randomized, crossover, ...
    • Prediabetes Is Associated with Increased Prevalence of Sleep-Disordered Breathing 

      Sánchez Peña, Enric; Sapiña Beltrán, Esther; Gavaldá, Ricard; Barbé Illa, Ferran; Torres, Gerard; Sauret, Ariadna; Dalmases, Mireia; López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira; Purroy Garcia, Francisco; Castro-Boqué, Eva; Farràs-Sallés, Cristina; Pamplona Gras, Reinald; Mauricio Puente, Dídac; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (MDPI, 2022)
      Type 2 diabetes leads to severe nocturnal hypoxemia, with an increase in apnea events and daytime sleepiness. Hence, we assessed sleep breathing parameters in the prediabetes stage. A cross-sectional study conducted on 966 ...
    • Severe alpha-1 antitrypsin deficiency in composite heterozygotes inheriting a new splicing mutation QOMadrid 

      Lara Gallego, Beatriz; Martínez, María Teresa; Blanco, Ignacio; Hernández, Cristina; Velasco, Eladio; Ferrarotti, Ilaria; Rodríguez, Francisco; Perez, Laura; Vazquez, Irene; Alonso, Javier; Posada, Manuel; Martínez-Delgado, Beatriz (BioMed Central, 2014)
      [Background]: Severe Alpha-1 Antitrypsin (AAT) deficiency is a hereditary condition caused by mutations in the SERPINA1 gene, which predisposes to lung emphysema and liver disease. It is usually related to PI*Z alleles, ...
    • Skin Autofluorescence Measurement in Subclinical Atheromatous Disease: Results from the ILERVAS Project 

      Sánchez Peña, Enric; Betriu i Bars, M. Àngels; Yeramian Hakim, Andree; Fernández i Giráldez, Elvira; Purroy Garcia, Francisco; Sánchez de la Torre, Manuel; Pamplona Gras, Reinald; Miquel, Eva; Kerkeni, M.; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (Japan Atherosclerosis Society, 2019)
      AIM: Advanced glycation end-products (AGEs) have been involved in the atherogenic process in the high-risk population. The goal of this study was to demonstrate that AGEs are related to subclinical atheromatous disease in ...
    • Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The ILERVAS project 

      Sánchez Peña, Enric; Lecube Torelló, Albert; Betriu i Bars, M. Àngels; Hernández, Cristina; López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Kerkeni, M.; Yeramian Hakim, Andree; Purroy Garcia, Francisco; Pamplona Gras, Reinald; Farràs-Sallés, Cristina; Fernández i Giráldez, Elvira; Barbé Illa, Ferran; Simó, Rafael (Elsevier, 2019-12-01)
    • Sympathetic Hyperactivity and Sleep Disorders in Individuals With Type 2 Diabetes 

      López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Sánchez Peña, Enric; González, Jessica; Yeramian Hakim, Andree; Martí, Raquel; Hernández García, Marta; Cao, Gonzalo; Ribelles, Mercè; Gómez Arbonés, Javier; Barril, Silvia; Barbé Illa, Ferran; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (Frontiers Media, 2019)
      Introduction: Many studies on the impact of type 2 diabetes mellitus (T2DM) on sleep breathing have shown a higher prevalence and severity of sleep apnea-hypopnea syndrome (SAHS) in those with T2DM. Moreover, an increased ...