Now showing items 1-8 of 8

    • Combination of biomarkers of vascular calcification and sTWEAK to predict cardiovascular events in chronic kidney disease. 

      Bozić Stanojević, Milica; Méndez-Barbero, Nerea; Gutiérrez-Muñoz, Carmen; Betriu i Bars, M. Àngels; Egido, Jesús; Fernández i Giráldez, Elvira; Martín-Ventura, JL.; Valdivielso Revilla, José Manuel; Blanco-Colio, LM. (Elsevier, 2018)
      BACKGROUND AND AIMS: Vascular calcification (VC) and atherosclerosis are associated with an increased cardiovascular morbimortality in chronic kidney disease (CKD). Osteoprotegerin (OPG) and osteopontin (OPN) are involved ...
    • Could IL-17A be a novel therapeutic target in diabetic nephropathy? 

      Lavoz, Carolina; Rayego Mateos, Sandra; Orejudo, Macarena; Opazo Rios, Lucas; Marchant, Vanessa; Marquez Exposito, Laura; Tejera Muñoz, Antonio; Navarro González, Juan F.; Droguett, Alejandra; Ortiz, Alberto; Egido, Jesús; Mezzano, Sergio; Rodrigues-Diez, Raul; Ruiz-Ortega, Marta (MDPI, 2020)
      Chronic kidney disease has become a major medical issue in recent years due to its high prevalence worldwide, its association with premature mortality, and its social and economic implications. A number of patients gradually ...
    • Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis 

      Marquez Exposito, Laura; Lavoz, Carolina; Rodrigues-Diez, Raul; Rayego Mateos, Sandra; Orejudo, Macarena; Cantero-Navarro, Elena; Ortiz, Alberto; Egido, Jesús; Selgas, Rafael; Mezzano, Sergio; Ruiz-Ortega, Marta (Frontiers Media, 2018)
      Chronic kidney disease (CKD) is emerging as an important health problem due to the increase number of CKD patients and the absence of an effective curative treatment. Gremlin has been proposed as a novel therapeutic target ...
    • IL-17A as a potential therapeutic target for patients on peritoneal dialysis 

      Marchant, Vanessa; Tejera Muñoz, Antonio; Marquez Exposito, Laura; Rayego Mateos, Sandra; Rodrigues-Diez, Raul; Tejedor, Lucia; Santos Sanchez, Laura; Egido, Jesús; Valdivielso Revilla, José Manuel; Fraser, Donald J.; López Cabrera, Manuel; Selgas, Rafael; Ruiz-Ortega, Marta (MDPI, 2020)
      Chronic kidney disease (CKD) is a health problem reaching epidemic proportions. There is no cure for CKD, and patients may progress to end-stage renal disease (ESRD). Peritoneal dialysis (PD) is a current replacement therapy ...
    • Paricalcitol Inhibits Aldosterone-Induced Proinflammatory Factors by Modulating Epidermal Growth Factor Receptor Pathway in Cultured Tubular Epithelial Cells 

      Morgado-Pascual, José L.; Rayego Mateos, Sandra; Valdivielso Revilla, José Manuel; Ortiz, Alberto; Egido, Jesús; Ruiz-Ortega, Marta (Hindawi Publishing Corporation, 2015)
      Chronic kidney disease is characterized by Vitamin D deficiency and activation of the renin-angiotensin-aldosterone system. Increasing data show that vitamin D receptor agonists (VDRAs) exert beneficial effects in renal ...
    • Soluble TWEAK and atheromatosis progression in patients with chronic kidney disease 

      Fernández-Laso, V.; Méndez-Barbero, N.; Valdivielso Revilla, José Manuel; Betriu i Bars, M. Àngels; Fernández i Giráldez, Elvira; Egido, Jesús; Martín-Ventura, JL.; Blanco-Colio, LM. (Elsevier, 2017-03-31)
      BACKGROUND AND AIMS: Circulating soluble TNF-like weak inducer of apoptosis (sTWEAK) concentrations are related to the presence of chronic kidney disease (CKD) and cardiovascular disease (CVD). However, there are no data ...
    • Soluble TWEAK and Major Adverse Cardiovascular Events in Patients with CKD 

      Fernández-Laso, V.; Sastre, Cristina; Valdivielso Revilla, José Manuel; Betriu i Bars, M. Àngels; Fernández i Giráldez, Elvira; Egido, Jesús; Martín-Ventura, JL.; Blanco-Colio, LM. (American Society of Nephrology, 2016-03)
      Abstract BACKGROUND AND OBJECTIVES: Soluble TNF-like weak inducer of apoptosis (sTWEAK) is a proinflammatory cytokine belonging to the TNF superfamily. sTWEAK concentrations have been associated with the presence of CKD ...
    • Vitamina D, receptor de la vitamina D e importancia de su activación en el paciente con enfermedad renal crónica 

      Bover, Jordi; Egido, Jesús; Fernández i Giráldez, Elvira; Praga, Manuel; Solozábal-Campos, Carlos; Torregrosa, José Vicente; Martínez-Castelao, Alberto (Sociedad Española de Nefrologia, 2015)
      El déficit de vitamina D se asocia a distintas patologías, siendo especialmente significativa con la morbimortalidad en pacientes con enfermedad renal crónica (ERC). La pérdida progresiva de la función renal conduce a ...