Now showing items 1-3 of 3

    • Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary 

      Gatius Calderó, Sònia; Cruz Paula, Arnaud Da; Silva, Edaise M. da; Segura, Sheila E.; Pareja, Fresia; Bi, Rui; Selenica, Pier; Kim, Sarah H.; Ferrando, Lorenzo; Vahdatinia, Mahsa; Soslow, Robert A.; Vidal, August; Przybycin, Christopher G.; Abu-Rustum, Nadeem R.; Matias-Guiu, Xavier; Rubin, Brian P.; Reis-Filho, Jorge S.; DeLair, Deborah F.; Weigelt, Britta (2020)
      Adult-type granulosa cell tumor (aGCT) is a rare malignant ovarian sex cord-stromal tumor, harboring recurrent FOXL2 c.C402G/p.C134W hotspot mutations in 97% of cases. These tumors are considered to have a favorable ...
    • Molecular Classification of Grade 3 Endometrioid Endometrial Cancers Identifies Distinct Prognostic Subgroups 

      Bosse, Tjalling; Nout, Remi; McAlpine, Jessica N.; McConechy, Melissa; Britton, Heidi; Hussein, Yaser; Gonzalez, Carlene; Ganesan, Raji; Steele, Jane C.; Harrison, Beth T.; Oliva, Esther; Vidal, August; Matias-Guiu, Xavier; Abu-Rustum, Nadeem R.; Levine, Douglas A.; Gilks, C. Blake; Soslow, Robert A. (Wolters Kluwer Health, 2018)
      Our aim was to investigate whether molecular classification can be used to refine prognosis in grade 3 endometrial endometrioid carcinomas (EECs). Grade 3 EECs were classified into 4 subgroups: p53 abnormal, based on ...
    • Redefining Stage I Endometrial Cancer: Incorporating Histology, a Binary Grading System, Myometrial Invasion, and Lymph Node Assessment 

      Barlin, Joyce N.; Soslow, Robert A.; Lutz, Megan; Zhou, Qin C.; St Clair, Caryn M.; Leitao, Mario M.; Iasonos, Alexia; Hensley, Martee L.; Barakat, Richard R.; Matias-Guiu, Xavier; Abu-Rustum, Nadeem R. (BMJ Publishing Group, 2013)
      Objective: We propose a new staging system for stage I endometrial cancer and compare its performance to the 1988 and 2009 International Federation of Gynecology and Obstetrics (FIGO) systems. Methods: We analyzed patients ...